| Objective:AMD through research Tianmagouteng drink to Pinggan yang, nourish liver and kidney of the treatment of hypertension clinical Hyperactivity of study insulin resistance and hypertension relation between hyperactivity of liver yang, confirmed that the side of the efficacy and safety, promotion of Chinese medicine preparation for the AMD based applications.Methods:1.Be patient with Hypertension 60 cases were randomly divided into 2 groups,treatment group 30 cases,30 cases of control group;the two groups in age, gender, disease duration, symptom scores, such as insulin resistance index compared There was no statistical significance (P> 0.05), comparable;control group:conventional western medicine treatment, (Iodine on the benzene of the ammonia chlorine flat)5mg, po, qd (from beijing, the department of the pharmaceutical industry limited liability company to provide product batch number:0910015)added services such as drinking Tianmagouteng Decoction (Gastrodia 10g, Uncaria 10g, abalone 20g, Cyathula 10g, Loranthaceae 10g, Eucommia ulmoides 10g, Shan Gardenia 10g, Scutellaria 9g, Motherwort 15g, Poria 10g, night Kodo 10g)300ml,each oral 150ml,2 times a day. Treatment groups:control group with western medicine,plus drink service Tianmagouteng AMD (Gastrodia 10g, Uncaria 10g, abalone 20g, Cyathula 10g, Loranthaceae 10g, Eucommia ulmoides 10g, Shan Gardenia 10g, Scutellaria 9g, Motherwort 15g, Poria 10g, night Kodo 10g) according to the corresponding dose ratio for each herb, except Gastrodia 2 package, the rest are a package, these drugs every taste ultra formula (IX Meeting of modern medicine in Hunan Spring Co.,Ltd.Production) Stir melted 300ml warm water added after each oral 150ml,2 times a day. Treatment for 2 weeks.2.Observed before and after treatment of symptoms and signs, the total efficiency, and do statistical analysis to compare its efficacy.3.Laboratory blood, urine, stool,ECG, liver function, kidney function as a safety index.4.The two groups before and after treatment fasting plasma glucose (FPG),fasting serum insulin (FINS).Fasting blood glucose with glucose oxidase method, insulin was detected by radioimmunoassay, insulin resistance index (IR) formula used HaffnerSM[19]and other proposed IR=(FPG*FINS)/22.5 calculated.Results:1.The two groups after treatment, the treatment group the total effective rate was 93.33%;control group 80.00% efficiency;improve the efficacy of clinical symptoms between the two groups was statistically significant difference (P<0.05),shows improvement of the treatment group in Chinese symptoms than the control group. 2.Before treatment, treatment and control groups can significantly reduce the symptom score, the difference was statistically significant (P <0.01).Between the two groups after treatment, the treatment group significantly reduced the symptom score than the control group, the difference was statistically significant (P<0.01).Explain the treatment group,the symptom score reduction is better than the control group.3.Pteris vittata 1.treatment group and the hook with a vinecontrol group rink of the lower blood pressure and diastolic pressure (contraction)role(p<0.01),two groups to reduce blood pressure and diastolic pressure(contraction)role of the statistical analysis showed a drink treatment group pteris vittata 1.the group and control group hook up the pressure of the role of difference there is no statistical significance(p>0.05)4.Omparing the two groups before and after the group, treatment group and control group IR changes were statistically significant (P <0.01).Between the two groups after treatment, the treatment group and control group IR changes were statistically significant (P<0.01).5 The treatment group and control group all the cases, blood, urine, stool,liver function, kidney function, and electrocardiogram before and after treatment showed no significant change in results.Description Decoction on blood, liver function, kidney function had no apparent side effects,no no gastrointestinal side effects such as to prove Tianmagouteng drink in this study is safe.Conclusion:1.Decoction on with Hypertension have the exact effect, can alleviate the symptoms with Hypertension and improve the TCM.2.Pteris vittata 1.tianmank on the illness is a definite effect and lower blood pressure.3.Gastrodia and Uncaria Decoction can improve insulin resistance (IR), Hyperactivity of the clinical symptoms improved, suggesting that insulin resistance with Hypertension is a pathological basis.4.Tianmagouteng drink with Hypertension the treatment safe and effective drug. |
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