Using Speckle Tracking Imaging To Evaluate Myocardial Strain And It's Relationship With Early Phase Left Ventricular Remodeling In Patients With Acute Myocardial Infarction

Objective Using speckle tracking imaging (STI) to assess the relationship between left ventricular deformation and remodeling in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention ( PCI) .Methods①The apical 4 chambers, 3chambers,2 chambers, long axis views of two-dimensional imaging were acquired in 30 healthy individuals and 40 patients with AMI after PCI. Peak strain (SL), peak longitudinal strain rate (SrL), global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) in systole were calculated for left ventricular segments by two-dimensional strain workstation.②To analysis relationship between two dimensional strain parametres and left ventricular end systolic volume (LVESV), left ventricular end diastolic volume (LVEDV), left ventricular ejection fraction (LVEF) .Results①In comparison with normal group, SL and SrL in AMI group decreased significantly, especial delayed PCI group.②LVESV, LVEDV increased markedly (P<0.05), LVEF decreased significantly (P<0.05), especial delayed PCI group.③There are good relationship between global strain parametres and LVESV, LVEDV, LVEF.④global longitudinal strain (GLS)≥-16%, the diognosis sensitivity and specificity of Left ventricular remodeling are 83.3% and 80%, global longitudinal strain rate≥-1.05 S^-1, the sensitivity and specificity are 83.3% and 83.3% .Conclusion①Speckle t racking imaging can quantitatively assess regional and global myocardial systolic deformation and function, also there are good correlations between two dimensional strain parameters and left ventricular remodeling indicators.②global longitudinal strain (GLS)≥-16%, the diognosis sensitivity and specificity of Left ventricular remodeling are 83.3% and 80%. global longitudinal strain rate≥-1.05 S^-1, the sensitivity and specificity are 83.3% and 83.3%.③Coronary recanalization after AMI can prevent the Left ventricular deformation and remodeling effectively.