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Comparison Of Wavefront Aberration In Pseudophakia With Different Types Of Intraocular Lenses

Posted on:2010-05-22Degree:MasterType:Thesis
Country:ChinaCandidate:H S BiFull Text:PDF
GTID:2194330332474949Subject:Traditional Chinese Medicine
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Objective:To compare high-order aberrations in patients who had cataract surgeryand implantation of different types of intraocular lenses (IOLs). in order to obtain an objective evaluation of the optical quality of these pseudophakic eyes.Methods:This prospective study comprised 120 cataract patients(198 eyes) who had phacoemulsification surger The optical aberrations were measured with the Hartmann-Shack wavefront sensor before and after surgery using a 5.0 mm and 6.0 mm wavefront aperture diameter for all comparisons. This study were divided into 3 fraction according to the type of IOL. A control group of 30 eyes of 15 elderly patients with normal crystalline lenses had the same examination. Primary part accoding to the material type of IOL were divided into 3 groups;second part accoding to the design shape of IOL were divided into aspherical and spherical intraocular lenses groups;third part evaluate early visual quality and wavefront aberrations of multifocal intraocular lens and single-focal intraocular lens for the treatment of cataractResults:Primary part three group was no statistical difference in high-order aberrations betweent the 2 acrylic IOL groups (P>0.05) However, the measured high-order aberrations were significantly higher in the 2 acrylic IOL groups than in silicone IOL groups (P<0.05).The total high order aberrations in hydrophobic acrylic lens group was higher than silicone group(P<0.05), but hydrophilic acrylic lens and hydrophobic acrylic were no significant difference. second part, there was a statistically significant between-group difference in contrast and glare sensitivity under visual angle 2.5°~1.6°,1.0°~0.7°.The difference in higher-order aberration (HOA) values between groups was statistically significant with a 5.0 mm and 6.0 mm pupil, with the AcrySof IQ IOL inducing less HOA than the AcrySof Natural IOL. Eyes with an AcrySof IQ IOL also had statistically significant less spherical aberration than eyes with an AcrySof Natural IOL with both pupil diameters (P<0.001). third part Percentage of patients with uncorrected near visual acuity 0.5 or better and 1.0 or better accounted 92.7%(51/55),38.2%(21/55) in the ReStor group and 36.4%(20/55),0.0%(0/55) in the control group, there was a significantly statistical difference between these two groups 3 months postoperatively(P<0.05).There was no significantly statistical difference between the corrected near and far visual acuity,and uncorrected far visual acuity of these two groups(P>0.05). In patients with visual acuity 0.5 or better, the depth of focus was (4.87±1.09)D in the ReStor group and was (2.08±0.69)D in the control group, there was a significantly statistical difference between these two groups (P<0.05). There was no significantly statistical difference between the preoperative corneal astigmatism and corneal astigmatism 1 week,1 month and 3 months after the operation in both groups (P>0.05). There was no significantly statistical difference in low,medium and high frequency contrast sensitivity and glare sensitivity, visual field between these two groups, respectively. (P>0.05). There was significantly statistical difference between the spherical aberration of ReStor group (-0.20±0.11)um and that of control group(0.27±0.13)um (t=-3.05, P<0.05). The percentage of patients with spectacle freedom in the ReStor group[85.4%(47/55)] is significantly higher than that in the control group [9.1%(5/55)] (P<0.05). Higher satisfaction was found in the ReStor group[89.1%(49/55)] than that in the control group[32.7%(18/55)] (P<0.05). One patient of every group complained glare at night, others were satisfied.Conclusions:There was a statistically significant increase in aberrations in patients with anacrylic IOL compared to those with a silicone.The results suggest that there is no difference in the retinal image of pseudophakic eyes with 3 types of IOLs in regular condition.The exact mechanism is uncertain. Further study is required to optimize IOL design.
Keywords/Search Tags:Intraocular Lenses, Wavefront, Ray Tracing, Contrast Sensitivty, Glare Sensitivty
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