Constipation Capsule Preparation Process And Quality Standards

The traditional Chinese medicine think that some etiology can cause maladjustment of function of colorectal transduction which can be initiated constipation,sone common etiology like these colorectal dryness genee, qi blood and body fluid insufficiency, old higher feebleness etc,which can be cause constipation,then constipation can be connected with lung,spleen,liver and renal, the disease locate the lower energizer of xiajiao colon. The treatment of constipation main lies in purgative activity,but it is unsuitable to abuse purgation drugs ,for example rhubarb,mirabilite,senna etc. At present, western medical is still not satisfied, and the result of treatment which uses Chinese traditional medicine is very good. There are many Chinese traditional medicine that can treat constipation in the market, such as Maren Pill, tongbianling Pill and etc. the experiment analyzed the clinical experienced prescription, do the experiment on extraction and preparation. established the quality standard from Chp. Part 4 and other documents, checked the stability to prove that the preparation is workable . The result is: angelica sinensis and atractylodes use 16 hours to extract volatile oil, and use aqueous solution-stirring method to include the volatile oil. In this condition, we can get the highest extracted and included rate. senna,atractylodes,hawthorn and the gruff of angelica sinensis and atractylodes adding quantity of 8 times 50% ethanol boil three times to fry, 1.5 hours every boiling time, the extractive rate is highest; established two TLC discriminations, five projects of checking and a content determination standard; It is reasonable and feasible to preparation technology and it is stable and dependable to standard quality though preparation technology and quality standard study. so, It is fit for manufacturing on large scale.