Study Of Preparation And Quality Standard Of Miniaoming Capsule

Miniaoning capsule is a compound pharmaceutics of modern traditional Chinese medicine prepared by scientific formula and technology and consisted of Chinese Thorowax Root, Schisandra chinensis (Turcz.) Baill., common Knotgrass Herb, Cortex Phellodendri, Radix Angelicae Sinensis, Himalayan Teasel Root, Taxillus chinensis (DC.) Danser, Semenabutili and Radix Glycyrrhiza. It is prepared by revising Keli to capsule and based on the same prescription and usage. The medicine has effect on relieving pain, and it treats heat stranguria, ache when urinating and the infection of urinary system in clinic.Based on the same technology, the study performed orthogonal experiments on water consumption, dewaxing time and dewaxing frequency in the dewaxing technology. The optimal conditions were that the medicine was decocted two times, the weight of water was 8 times as large as that of the medicine, and the first and second step lasted for 2h and 1.5h, respectively.When the quality standard was studied, the examination of general items were proceeded according to the pharmacopoeia, including water content, content uniformity, disintegration, heavy metal and arsenic salt. The identification tests of Chinese Thorowax Root, Cortex Phellodendri and Radix Angelicae Sinensis were added, and the method that the content of Glycyrrhizic Acid in Miniaoning capsule was determined by HPLC was established. Therefore, the medicine quality standard was improved.The scientific foundation was offered for the production, package, preservation and transportation of Miniaoning capsule by studying the acceleration and long-term stability, and the validity period of the medicine was defined.