Multi-States Biomolecular Autonomous Computer Applying In Leukaemia

We first introduce the basic theory of determined and non-determined automaton, and the pre-knowledge of gene diagnosis and therapy, and then we consult Yaakov Benison's autonomous mechanism and design a multi-states non-determined automaton, which use the model of leukaemia.The model in this article adopts the mechanism of Yaakov Benison's molecule doctor. The autonomous computer designed by Yaakov Benison is a two-states non-determined automaton, which only for gene diagnosis and therapy of one disease. Actually, one disease may have different sub-types, and one gene may have effect on the diagnosis of different diseases, so it's very necessary to design multi-states non-determined automaton. According to this, we design a multi-states non-determined automaton, which use the model of leukaemia and we also give the concentration model of this molecule automaton.The multi-states biomolecular automaton applying in leukaemia in this article implements the computer by a sophisticated use of the restriction enzyme which can cut on both sides. It's model is leukaemia, which have different sub-types and one gene has effect on different diseases'diagnosis. This automaton can implement diagnosis and therapy of three sub-types of leukaemia at the same time, of which one gene has effect on the diagnosis of one or more sub-types. The automaton also can release more than one type drugs.