Study On The Regularity Of Traditional Chinese Medicine In Treating Chronic Obstructive Pulmonary Disease

Purpose:Based on literatures of chronic obstructive pulmonary disease in recent 10 years, combing the medication rule of traditional Chinese medicine in the treatment of chronic obstructive pulmonary disease, in order to provide the basis of literatures for clinical medication of chronic obstructive pulmonary disease.Material and method:Based on CNKI database, using “chronic obstructive pulmonary disease”, “COPD” and “lung distention”, respectively, contains “Chinese medicine ",“Chinese herbal medicine” and" traditional Chinese medicine " as theme words to collect the related 4647 articles on TCM treatment of chronic obstructive pulmonary disease for recent 10 years. According to the inclusion criteria and exclusion criteria, select the AECOPD 80 articles, stable stage 58 articles, sum to 138 articles. Extracting Chinese prescription, type of syndrome, Chinese medicine and drug properties, taste, meridian entry from 138 articles, to establish EXCEL table,using frequency statistics method and cluster analysis method to analyze the efficacy, the nature,taste, meridian of medicine and general medicine of the medicines using during acute exacerbation phase and stable phase and the medicines using in both phases. Meanwhile, using cluster analysis to analyze the drugs is used for equal or greater than 15 times. Finally summarize the medication rule of traditional Chinese medicine in the treatment of chronic obstructive pulmonary disease in recent 10 years.Results:1. This study collected 138 articles in decoction majority, syndrome differentiation type mainly based on phlegm heat obstructing lung, the study totally collected 145 drugs, a total of 1577 times of medicine.The drug properties of the traditional Chinese medicines in the treatment of chronic obstructive pulmonary disease were mainly cold, warm, flat; the drug taste were sweet, bitter, acrid; the drug meridian entry were lung, liver, spleen, stomach, kidney and heart; the application frequency of the top 6 medical efficacy category descendingly are phlegm cough antiasthmatic, tonic drug, heat-clearing drug, drug for invigorating blood circulation and eliminating stasis, drugs for relieving exterior syndrome, diuretics for eliminating dampness; the application frequency of 10 drugs by descending order followed by Gancao, Banxia, Fuling, Chenpi, Kuxingren, Huangqin, Huangqi, Gualou, Danshen, Baizhu.2. The study collected 107 drugs, a total of 881 times of medicine on the acute exacerbation period of Chronic obstructive pulmonary disease. The drug properties of acute exacerbation period of chronic obstructive pulmonary disease medication were mainly cold, warm, flat; the drug taste were bitter, sweet, acrid; the durg meridian entry were lung, liver, spleen, stomach, heart, and kidney; the application frequency of the top 6 medical efficacy category descendingly are phlegm cough antiasthmatic, heat-clearing drug, tonic drug, drug for invigorating blood circulation and eliminating stasis, drugs for relieving exterior syndrome,diuretics for eliminating dampness; the application frequency of 10 drugs by descending order followed by Gancao, Kuxingren, Huangqin, Banxia, Gualou, Beimu, Jiegeng, Fuling, Chenpi, Sangbaipi.3. The study collected 116 drugs, a total of 696 times of medicine on the stable period of Chronic obstructive pulmonary disease. The durg properties of stable period of chronic obstructive pulmonary disease medication were mainly warm, cold, flat; the drug taste were sweet,bitter, acrid; the drug meridian entry were lung, spleen, kidney,liver, stomach, and heart; the application frequency of the top 6 medical efficacy category descendingly are tonic drug, phlegm cough antiasthmatic,diuretics for eliminating dampness, drug for invigorating blood circulation and eliminating stasis, drugs for relieving exterior syndrome, drugs for regulating QI flow; the application frequency of 10 drugs by descending order followed by Gancao, Fuling, Huangqi, Baizhu, Chenpi, Banxia, Danshen, Dangshen, Wuweizi, Danggui.4. Cluster analysis was performed 5 class of drugs: 1.Gancao, Banxia, Fuling, Chenpi, Huangqi, Baizhu,Dangshen, Shanyao, Shudi. 2.Kuxingren,Huangqin,Gualou,Beimu, Jiegeng, Sangbaipi, Zisuzi, Yuxingcao, Zhishi, Ziwan, Kuandonghua, Maidong. 3.Danshen, Tinglizi. 4.Taoren, Danggui, Chuanxiong. 5. Mahuang, Wuweizi, Dilong, Guizhi.Conclusion:1.Recently 10 years literature suggested efficacy category of drug that traditional Chinese medicine treating chronic obstructive pulmonary disease were mainly phlegm cough antiasthmatic,tonic drug, heat-clearing drug.2.Recently 10 years literature suggested efficacy category of drug that traditional Chinese medicine treating acute exacerbation period of chronic obstructive pulmonary disease were mainly phlegm cough antiasthmatic, heat-clearing drug, tonic drug.3.Recently 10 years literature suggested efficacy category of drug that traditional Chinese medicine treating stable stage of chronic obstructive pulmonary disease were mainly tonic drug, phlegm cough antiasthmatic,diuretics for eliminating dampness.4.Cluster analysis shown that traditional Chinese medicine treating chronic obstructive pulmonary disease were mainly phlegm cough antiasthmatic,tonic drug, heat-clearing drug, drug for invigorating blood circulation and eliminating stasis, drugs for relieving exterior syndrome in the literature recently 10 years.