Study On The Correlation Between Vitamin D Level And TCM Syndromes Of Type

Objective:To observe vitamin D levels of type 2 diabetes with different TCM syndromes,and to explore correlation between vitamin D levels and TCM syndrome of type 2 diabetes.Method:This study adopts the method of epidemiological cross-sectional study. Collected 231 outpatients and inpatients with type 2 diabetes from endocrinology and nephrology department of Wangjing Hospital of CACMS in July 2014 to October and in July 2015 to October. Divided them into deficiency of yin and excessive heat group, damp-heat accumulation group, qi-yin deficiency group, yin-yang deficiency group and blood stasis context group by TCM syndrome.Then recorded five groups of patients with serum vitamin D levels and gender, age, course of disease, etc.And to explore the correlation between vitamin D levels and TCM syndrome of type 2 diabetes.ResultsrThe study included 231 patients with type 2 diabetes. There were male 117 cases and female114 cases, male and female ratio of 1.03:1.The study of patients aged 40 years minimum, maximum age 70 years.Statisticsed TCM syndrome in231 patients of type 2 diabetes show that deficiency of yin and excessive heat group 45 cases, accounting for 19.48%; damp-heat accumulation group 58 cases, accounting for 25.11%; qi-yin deficiency group 70 cases, accounting for 30.30%;yin-yang deficiency group 30 cases, accounting for 12.99%; and blood stasis context group 28 cases, 12.12%.1.In terms of gender,there is no significant difference among deficiency of yin and excessive heat group, damp-heat accumulation group, qi-yin deficiency group, yin-yang deficiency group and blood stasis context group (P>0.05).2.In terms of age, qi-yin deficiency group older than deficiency of yin and excessive heat group,younger than yin-yang deficiency group and blood stasis context group.There is no significant difference between deficiency of yin and excessive heat group and damp-heat accumulation group(P>0.05). There is no significant difference between damp-heat accumulation group and qi-yin deficiency group(P>0.05). There is no significant difference between yin-yang deficiency group and blood stasis context group(P>0.05).3.In terms of the course of the disease, qi-yin deficiency group longger than deficiency of yin and excessive heat group and damp-heat accumulation group, shorter than yin-yang deficiency group and blood stasis context group.There is no significant difference between deficiency of yin and excessive heat group and damp-heat accumulation group(P>0.05). There is no significant difference between yin-yang deficiency group and blood stasis context group(P>0.05).4. Complications of each TCM syndrome:blood stasis context group complicated with diabetic peripheral neuropathy the most, and yin-yang deficiency group, qi-yin deficiency group, damp-heat accumulation group, deficiency of yin and excessive heat group in turn reduce.Yin-yang deficiency group complicated with diabetic nephropathy the most, followed by reduction of blood stasis context group, qi-yin deficiency group, damp-heat accumulation group, deficiency of yin and excessive heat group. Blood stasis context group complicated with hypertension the most, yin-yang deficiency group, qi-yin deficiency group, deficiency of yin and excessive heat group, damp-heat accumulation group successively reduced. Blood stasis context group complicated with hyperlipidemia the most, yin-yang deficiency group, heat damp-heat accumulation group, qi-yin deficiency group, deficiency of yin and excessive heat group in turn reduce.5. hemoglobin glycosylated and fasting plasma glucose of each TCM syndrome: deficiency of yin and excessive heat group< heat damp-heat accumulation group< qi-yin deficiency group< yin-yang deficiency group and blood stasis context group. There is no significant difference between yin-yang deficiency group and blood stasis context group(P>0.05). There is no significant difference in calcium among five groups (P> 0.05).6. Vitamin D levels of the each TCM syndrome:deficiency of yin and excessive heat group>damp-heat accumulation group>qi-yin deficiency group>defi- -ciency of both yin and yang group and blood stasis context group.There is no significant difference between yin-yang deficiency group and blood stasis context group(P>0.05).The level of vitaminD of deficiency of yin and excessive heat group, damp-heat accumulation groupand qi-yin deficiency group mainly in the absence level. The level of vitaminD of yin-yang deficiency group and blood stasis context group mainly in the serious absence level.7.Using polytomous variable and multivariate Logistic regression analysis factors related to vitamin D levels.The results showed that the distribution of vitamin D levels associated with gender, age, course of the disease, TCM type(P<0.05).Using polytomous variable and multivariate Logistic regression analysis factors related to TCM syndrome. The results showed that TCM syndrome associated with course of the disease and vitamin D levels (P<0.05),and regardless of gender and age (P>0.05).Conclusions:1.Vitamin D levels in patients with type 2 diabetes is generally low. VitaminDlevelsof deficiency of yin and excessive heat group,damp-heat accumulation group and qi-yin deficiency group mainly in the absence level. Vitamin D levels of yin-yang deficiency group and blood stasis context group mainly in the serious absence level. Vitamin D levels of the each TCM syndrome:deficiency of yin and excessive heat group>damp-heat accumulation group>qi-yin deficiency group>yin-yang deficiency group and blood stasis context group. There is no significant difference between yin-yang deficiency group and blood stasis context group(P>0.05).2. The distribution of vitamin D levels in patients with type 2 diabetes associated with gender, age, course of the disease, TCM type. Simultaneously TCM syndrome associated with course of the disease and vitamin D levels.3.For vitamin D deficiency in patients with type 2 diabetes,should provide timely intervention.For example, to supplement vitamin D by increasing the duration of sunshine, lifestyle changes, oral vitamin D and other ways. The purpose is to mitigate the effects of vitamin D deficiency in patients with type 2 diabetes.At the same time by correcting vitamin D deficiency, in order to some extent improve the syndromes of patients with type 2 diabetes.