Full-field White-light PS-OCT With A Linnik Microscope

Optical coherence tomography (OCT) combines the advantages of confocal microscopy and low-coherence interferometry to produce noninvasive high-resolution cross-sectional images of internal microstructure of living tissue. OCT demonstrates its great potential in clinic biopsy and microsurgical, where OCT images are severely important. But still there are many limitations of OCT, such as limitation in penetration, resolution, acquisition rate, image contrast, 2D digital images in facultative angle and stratum. Only when these parameters are extraordinarily satisfactory for biopsy can it prevent catastrophic consequences and reduce iatrogenic injury.This paper manages to set up a more completed OCT system that can satisfy the need of clinic biopsy and microsurgical.This dissertation introduces the basic technology and the evolution of optical coherence tomography (OCT), analyses OCT advantages and disadvantages, investigates the effects of numerical aperture of imaging lens (NA) and time gate on the OCT imaging, and brings forward full-field white-light PS-OCT with a Linnik microscope to advance OCT capability.This system and principle based on confocal microscopy are adequately studied and tell how to pick-up information of bio-tissue from CCD signal. Full-field white-light PS-OCT with a Linnik microscope can study the envelope of CCD signal and phase signal from sample arm to find information of tissue topography and birefringence using phase modulation technique.