Effct Of The Seasonal Variation On The Sleep Breathing Of Patients With Cerebral Infarction

Objective: To explore the effct of the seasonal variation on the cerebral infarction patients with sleep apnea.Methods: All of patients with cerebral infarction in more than three weeks and less than 3 months diagnosed by cranial CT or MRI and high risk group underwent polysomography (PSG) in different seasons.Comparing the effct of seasonal variation on the apnea and hyponea index (AHI), the lowest oxygen saturation (LSaO2) and the longest apnea time (Longest events). All patients were divided into obstructive sleep apnea hyponea syndrome group (OSAHS group) or non-OSAHS group according to the diagnosis of PSG.Results: 49 of 55 patients were selected .All of them were divided into two groups.25 cases of cerebral infarction group,of which 17 cases OSAHS subgroup,8 cases of non-OSAHS subgroup; 24 cases of high-risk group, of which 17 cases OSAHS subgroup, 7 cases of non-OSAHS subgroup.AHI of OSAHS subgroup of cerebral infarction group for the winter-spring was 14.75±2.55, while in summer was 20.44±2.77;non-OSAHS subgroup was respectively 1.81±0.59, 1.99±0.62; OSAHS subgroup of high-risk group was respectively 38.32±5.79, 45.65±5.27, non-OSAHS subgroup was respectively 2.82±0.46, 2.83±0.40. The differences of AHI between winter-spring and summer in OSAHS subgroup was statistically significant (P<0.05),but the difference of the lowest oxygen saturation (LSaO2) and the longest apnea time (Longest events) had no statistically significant (P> 0.05).In contrast, the differences of the three indicators of non-OSAHS subgroups had no statistically significant.Linear regression analysis showed that△average atmospheric pressure and△AHI has a negative correlation, and effect of atmospheric pressure on cerebral infarction group was greater than high-risk group.Conclusions: Summer can increase sleep-disordered breathing in patients with OSAHS. Variation of atmospheric pressure may be the main factors of sleep-disordered breathing.