Evaluate The Effect Of SXBXW For Patients With Acute Myocardial Infarction After PCI

Objective:evaluate the effection of SXBXW in acute myocardial infarction(AMI) after percutaneous coronary intervention(PCI) successfully. Methods: By randomized controlled method,60 cases met the criteria of acute myocardial infarction were randomly divided into treatment group(n=30) and control group(n=30). They were both treated with conventional western medicines base on the guidline,mainly including:clopidogrel bisulfate 75mg qd, enteric-coated aspirin 300mg qd(100mg 2-month later), atorvastatin 20mg qn, Bisoprolol fumarate 2.5mg qd (if situation allowed, increase the amount to 5mg qd), Captopril 12.5mg tid (based on monitoring blood pressure, if allowed,increase the amount to 50mg tid);the treated group plus SXBXW,2 capsules each time,3 times a day, two groups both 6-month, If enrolled patients have other diseases, added correspondent drugs according to the relative guideline.The following index were observed:Seattle Angina Questionnaire(SAQ), NT-Pro-BNP, high-sensitive C-reactive protein. (hs-CRP) and LVEF(%).Result:Both two groups'PL, AS, AF, TS,DP of SAQ are improved than them before PCI, it has statistics significance and PL, AS, AF of treated group are more elevated than control group, the difference has statistics significance(p<0.05).After 6 months'treament, NT-Pro-BNP of both patients in treated group and control group declined greatly, It has statistics significance(p<0.05), compared treated group with control group, it has statistics difference (p<0.05).LVEF of the patients in treated group and control group have distinct improvement after PCI six-month later. It has statistical significance(p<0.01), compared treated group with control group, it is non-statistics difference (p>0.05),it maybe influed by short-period of treatment.The Hs-CRP of 6 months later is distinctly lower than it before the PCI. It has statistics significance(P<0.05), but compared treated group with control group,it is non-statistics difference(p>0.05).Conclusion:patients with AMI after PCI successfully who treated with SXBXW can more effectively control the symptoms of angina, improve the quality of life,reduce NT-Pro-BNP,Hs-CRP values and improve LVEF,improve the prognosis of patients with AMI after PCI successfully.