| Objective: The incidence of degenerative lumbar scoliosis(DLS) was accounted for 6% of degenerative lumbar diseases. DLS is a complex spinal deformity, not only for the coronal plane bending, but often associated with vertebral axial rotation, lateral shift of coronal plane and frontal displacement of sagittal plane. Ratio between male and female was 1:2. It is often caused by osteoporosis and degeneration of intervertebral disc and facet joint. Decreased bone density was initially considered to be the important cause of DLS, severe osteoporosis will accelerate the development of degenerative lumbar scoliosis. It is reported that women with postmenopausal osteoporosis have significantly higher incidence of DLS than those without osteoporosis. DLS can also be secondary to osteoporotic compression fractures, non-symmetry of the compression fracture can increase the degree of scoliosis. patients with degenerative lumbar scoliosis often have a wider range of disc degeneration, facet joint hyperplasia, hypertrophy of ligamentum flavum, spinal instability when assosiated with osteoporosis, usually accompanied with lateral displacement of the spine coronal plane, rotation, subluxation and olisthesis. At the same time, osteoporosis, muscle strain, trunk loss of balance, loss of lumbar lordosis, facet joint disease, spinal stenosis and other factors will together increased patients'low back pain. The study is committed to master the correlation of DLS and osteoporosis through the statistical analysis of BMD and T values, then to supply a theoretical basis for preoperative and postoperative treatments, optimize the suigical programs, and decrease the complications on and after surgery. Meawhile, mastering the incidence of degenerative assosiated osteoporosis could give health guidances, stressed the importance of anti-osteoporosis especially for the elderly, an prevent the occurrence of degenerative lumbar scoliosis on some extent. Method: From Oct.2007 to May.2010, 69 patients diagnosised with degenerative scoliosis from out-patient and wards were included in the group. There were 6 males and 63 females with an average age of 69.3 years(ranged from 58 to 81 years). To comfirm the diagnosis, all the patients underwent X-Ray , CT and MRI examines, several patients underwent myelography, Cobb's angle was recorded respectively. Control group had 50 cases without scoliosis, including 37 spinal stenosis, 8 lumbar disc herniation, 4 spondylolisthesis and 1 lumbar spinal tumor. The bone density of lumbar(L2-4) and proximal femoral regions was measured with dual-energy x-ray absorptiometry. BMD and T values were recorded. The change of T values of diffierent ages and Cobb angles was observed to analyze the ralationship between them. Statistical analysis were performed with SPSS 13.0.Result: Of the 69 cases with degenerative scoliosis, the average T-score was -2.8±1.9(distributed from -0.9 to -4.7), 52 cases combined with osteoporosis, 14 cases combined with osteopenia, the incidence of osteoporosis was 75.4%, the incidence of osteopenia was 17.4%; the average T-score in the control group was -0.6±1.8(distributed from 0.4 to -2.8), 5 cases combined with osteoporosis, 17 cases combined with osteopenia, the incidence of osteoporosis was 10%, the incidence of osteopenia was 34%. Significant difference was found among the mean t-scores of lumbar and proximal femoral regions of the groups(p<0.05). According to the comparision of T-score in different ages and Cobb's angles, the T-score has a positive correlation with age, and zero correlation with Cobb's angle.Conclusion: Osteoporosis is a risk factor for degenerative scoliosis, there exists a significant correlation, in this cohort the incidence is 75.4%. Curve magnitude doesn't correlate with the severity of osteoporosis.
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