The Academic And Clinical Investigation On The Pathogenicity Of Wind On Children's Henoch-Schonlein Purpura

Objective:Through clinical analysis of Henoch-Schonlein Purpura of children, the subject study the characteristics of the disease, in order to look for a new theory on etiology, pathogenesis and therapeutics in Traditional Chinese Medicine. It can make treatment by pathogenic wind an important way, in that conditions, clinical curative effect can be improved, the complications and recurrence can be reduced.Methods:Adopting the approach of retrospective study, we establish studying standards, collect the cases of patients who are in Jiangsu Province Hospital of Traditional Chinese Medicine from Mar.2008 to Oct.2009, and select 60 cases up to standard in the end. And then collate information, observe the coincidences between the symptoms of the cases collected and pathogenic wind, study the mechanism of how it cause the disease; summarize representative therapeutics of that, common drugs, and treatment for consolidated-evil, statistic the match relationship of the therapeutic in the prescriptions.Results:A considerable part of the clinical manifestations of the disease are in line with the characteristics of "wind",which is a vital cause of Henoch-Schonlein Purpura. External wind is a prime motivation for this disease, In the course of disease, there are many "wind" and its consolidated-evil performance. Either pathogenic wind exists in every patter type, or its advance and retreat has prompted conversion of diseases and patter types. Referring to Chinese medicinal treatment for pathogenic wind, it includes scattering wind and relieving exterior, dispelling wind and drying dampness, dispelling wind and nourishing blood, dispelling wind and resolving toxins, dispelling wind and eliminate dampness, dispelling wind and invigorating blood, dispersing wind and alleviating itching, diffusing the lung and dispelling wind, clear liver heat and extinguish wind. Meanwhile take treatment according to pattern differentiation; for example, medicinals for clearing heat, drying dampness, resolving toxins, dissolving stasis, supplement deficiency. Among them, scattering wind and relieving exterior, dispelling wind and nourishing blood, dispelling wind and drying dampness, are the most commonly used.Conclusion:Pathogenic wind is a very important pathogenic factor of Henoch-Schonlein Purpura, it should not be ignored in theory of etiology and pathogenesis. The doctors should emphasize special therapeutics of pathogenic wind according to different stages, in order to take right measures to improve clinical efficacy.