The Clinical Investigation On Treating Auxiliary Of Unstable Angina By Tongluo Baoxin Paste

Object:Observe the effect of inhalling TONGLUO BAOXIN PASTE on symptom,ECG,myocardial oxygen consumption and total ischemia burden of the patients with Unstable Angina,evaluate the clinical curative effect of this method,and explore the potential function mechanism.Method:To investigate 80 patients with Unstable Angina diagnosed by coronary CTA or coronary angiography in the Traditional Chinese Medicine Hospital of XuZhou City which is the Afiliated Hospital of Nanjing TCM University.The 80 patients were divided into testing group and observing group with eaqual number.All the 80 patients were given basic treatment,but the testing group was treated with inhalling TONGLUO BAOXIN PASTE (the formula which is getted from the experience of Zhang PeiYing Professor is made in the Traditional Chinese Medicine Hospital of Xu Zhou City.) The period of treatment is 2 weeks. Compared the change of symptom,ECG,myocardial oxygen consumption and total ischemia burden before and after treatment.Reasults:The total effective rate of the treat group was 85.0%, and the control group was 82.5% with none significant difference(P<0.05), althought the later's effective rate was higher than the former.There were significant difference in some indices such as TIB in before and after treatments (P<0.05). The safety indices also had no obviouse changes in before and after treatments. Inhalling TONGLUO BAOXIN PASTE has marked helpful effect on Unstable Angina. It can reduce myocardial oxygen consumption and total ischemia burden noticeably.Conclusion:Clinical symptoms of the patients with Unstable Angina were treated by Inhalling TONGLUO BAOXIN PASTE can improved markedly.Especially,in the respect of improving obvious ictal frequency, degree, continuous time etc. The effect of reducing myocardial oxygen consumption and total ischemia burden is remarkable.In addition, Inhalling TONGLUO BAOXIN PASTE has function on protecting ischemic myocardium and improving the hypoxic endurance with myocardial cells, which can decrease the instant dangerous degree of myocardial ischemia event.