Initial Observation Of Macular Thickness After Phacoemulsification And Trabeculectomy By Optical Coherence Tomography

Objective:Observing changes of foveal retinal thickness after phacoe-mulsification and trabeculectomy by OCT.Method:In this study, we had token information of normal people and patients with glaucoma and cataract in Xiangya Hospital from Feb.2009 to Feb.2010 and analyzed foveal retinal thickness of 34 patients with cataract and glaucoma performed phacoemulsification and trabeculectomy(group A),45 patients with simply age-related cataract performed phacoemulsification(group B)and 48 patients with glaucoma performed trabeculectomy(group C).All the date on foveal retinal thickness would be measured by OCT and changes of that after 1 week and 4 weeks of postoperation, and the foveal retinal thickness of preoperative and 44 normal eyes(group D) would be collected and be analysized.Result:1.Foveal retinal thickness between experimental and control groups was no significant difference before operation(P>0.05).2.The macular retinal thickness of those patients, whose phacoemulsification and trabeculectomy were performed at the same time,increased significantly (p<0.05)in the first week and forth week after operation.3.The macular retinal thickness of the patients with only phacoemulsification increased in the first week and forth week after operation. But only the forth week after operation was statistically significantly different (p<0.05).4.The macular retinal thickness of trabeculectomy in the first week and forth week after operation was thicker than preoperative, but the difference was not statistically significant(P>0.05).The foveal retinal thickness of group A and froup B,group A and group C were different in the first week and forth week after operation, and the difference was statistically significant (p<0.05),However, group B and group C showed no statistically significant difference(P>0.05).5.The preoperative IOP and foveal retinal thickness of group A and group B were positively correlated(r=0.401,P=0.019 and r=0.382, P=0.007),but there was no correlation in group B(r=0.205,P=0.176).6.The postoperation vision and macular retinal thickness in the first week and forth weeks after operation were negatively correlated in group A(r=-0.423,P=0.013;r=-0.404, P=0.018).There was no correlation in group B and group C(r=0.008, P=0.957;r=0.220, P=0.147and r=-0.226,P=0.123;r=-0.160,P=0.277).Conclusion:1.After a phacoemulsification, the macular retinal thickness increased significantly and when the phacoemulsification and trabeculectomy were performed at the same time,it increased more.2.OCT is a simple, quick,non-invasive method for clinically observing early changes of foveal retinal thickness after phacoemulsification and trabeculectomy.