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Percutaneous Oxygen Partial Pressure And Type 2 Diabetes Vascular Lesions In The Analysis Of The Affecting Factors

Posted on:2011-11-16Degree:MasterType:Thesis
Country:ChinaCandidate:S LuoFull Text:PDF
GTID:2154360305494695Subject:Endocrinology
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Objective:Analyzed the relationship between TcpO2 and the influencing factors of the lower extremity vascular disease in type 2 diabetes.Methods:Choose 121 type 2 diabetes patients from the patients who were admitted into The Third Xiangya Hospital from 2009.12-2010.4.After finished physical examinations, biochemical examinations,Transcutaneous Oxygen Partial Pressure Determination and vascular doppler, according to the measured values those patients were divided into TcpO2 abnormal group and normal group, analysis the disease risk factor of lower extremity vascular disease in type 2 diabetes patients.Results:①47 routine TcpO2 determination<40mmHg,74 cases TcpO2 determination≥40mmHg. Two groups of vascular lesions related factors were analyzed, it showed that the level of HbAlc, umAlb,ABI, PBI in TcPO2 abnormalities group were higher than normal group, diabetic retinopathy retinopathy occurrence high in TcPO2 abnormalities group,statistically significant differences (P<0.05).②Research results showed that the determination of TcPO2 was relevant with HbAlc, umAlb and ABI, TBI, diabetic retinopathy. TcpO2 had positive correlation with HbAlc,umAlb,r value were-0.2513, -0.2134,respectively;And ABI, TBI, diabetic retinopathy was negatively correlated, and ABI, TBI r value were 0.4235 0.4924, respectively.Conclusion:The TcPO2 are relevant with HbAlc, umAlb and ABI, TBI, diabetic retinopathy. TcpO2 has positive correlation with HbAlc, umAlb, and ABI, TBI, diabetic retinopathy is negatively correlated.TcP02 reduction may be due to the peripheral vascular disease, also may be due to the organization and peripheral capillary pathological change.therefore, combined with TcP02 detection and ABI, TBI could reflect earlier vascular lesions comprehensively.
Keywords/Search Tags:Type 2 diabetes, lower extremity vascular disease, Transcutaneous Oxygen Partial Pressure Determination
PDF Full Text Request
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