Research Of Schisandra To Exercise Rat's Immune Function And Antioxidation In Formaldehyde Environment.

The world fitness club, professional sports stadiums are high-speed lots of emerging, but when people in luxury, beauty of fitness clubs and design fashion professional sports stadiums consumption exercise, the body has been fitness from invisible damage serious threat of source -- Formaldehyde. Long-term exposure in formaldehyde environment can cause dermatitis, its metabolites allergic diseases and reactive oxygen free radicals amino acids, protein, nucleic acid formed unstable binders, transferred to the kidney, liver and hematopoietic organization on the cardiovascular system, endocrine system, the digestive system, reproductive system, cause renal oxidative damage, and have certain genetic toxicity. For the traditional Chinese herbal medicine, Schisandrae application has a long history. Schisandrae can strengthen and regulate cardiomyocyte and heart small arteries energy metabolism, improve the myocardial nutrition and energy, improve the myocardial superoxide dismutase (SOD) and reduce lipid peroxide content and improve immune, resistant to oxygen and anti-fatigue capability against ring phosphoric acid amine, caused by the decrease and peripheral leukocytes prevention and treatment of cancer.This paper model body undertake aerobic exercise in different concentrations of formaldehyde poisonous indoor sports place, to establish and maintain smoked air (Moderate-Height two formaldehyde pollution concentration) and the device has run of machine, using a glass case of chronic animal experiment method, experimental animals exercise training. Experiment unifies physiology, biochemistry theory and sports biological sciences research methods and technology, application to rat immune index -- and its classification indexes, white T lymphocyte subsets, immunoglobulin, and brain, liver, skeletal antioxidant defense system, in both concentration formaldehyde inhaled the dynamic change regulation after the test analysis, this paper added after water decoction Schisandrae nutritional status of sports rats, sports ability, immune ability and brain, liver, skeletal muscle tissue of the influence of various antioxidant enzymes activity, for developing Schisandrae indoor air formaldehyde in to reduce the harm of sports population to provide the reference.Experiment MethodsSlect healthly Whister pure male rats, according to the department in 1996 issued by the bedroom of the formaldehyde in air hygiene standards "regulation bedroom and public places the allowable concentration formaldehyde in 0.08 mg/m~3 and 0.12 mg/m~3, respectively, for standard by 10 and the concentration of 20 times (0.8 mg/m~3 and 2.4 mg/m~3) create artificial Moderate-Height (Heavy) concentration formaldehyde poisonous environment. According to the experimental requirements , animals were randomized into eight groups: Normal Control (NC), Moderate Formaldehyde (MF), Heavy Formaldehyde (HF), Exercise Control (EC), MF+ Exercise (MFE), HF+ Exercise (HFE), MFE+Schisandra (MFES), HFE+Schisandra (HFES), 9 in each group only (8 only the last test, 1 only spare). Except NC and EC group, all groups in the corresponding formaldehyde environment. Exercise groups are on the run sets 20m/min, 30min/d, 6d/week for 4 weeks. Schisandrae to stomach after daily training of 1 hour, the rest of to stomach the equally volumetric water. Last week after training, the death of rats , determined spleen and thymus exp, WBC and subsets, T subgroup and immune globulin and cardio-cerebral, liver, skeletal superoxide dismutase (SOD), catalase (CAT) GSH peroxidase (GSH - Px) activity and malondialdehyde (MDA) content.Conclusion:1 Formaldehyde pollution environment have direct effects of the weight growth, heavy pollution than moderate pollution affects big, Formaldehyde exercise group than formal dehyde large; Taking schisandra can alleviate this weight loss.2 Formaldehyde environments will cause the immune organ damage and immune supperssion; schisandrae can shift the negative to the positive effect.3 The the exercise groups in formaldehyde, the immune function and antioxidant capacity lower than quiet group;4 Formaldehyde can cause rat tissue oxidative damage, cause antioxidant ability to drop, lipid peroxidation, cell metabolism environmental damage. Formaldehyde on the rats exercise group antioxidant capacity reduction is more obvious.Schisandrae water can effectively enhance the content of antioxidant enzymes, prompting antioxidant capability.5 Formaldehyde on the immune system NE, MO, EO content and brain GSH - PX content, liver tissue MDA value, skeletal muscle tissue of SOD content most sensitive, moderate pollution can cause significant damage. Schisandrae can improve immune system NE, LY, spleen T-cell subsets, IgG, brain tissue of SOD, liver and skeletal muscle tissue GSH - PX content than any other organization improve significantly.