| In this study, the genome of the first strain of HAstV1 in shanghai was cloned, and which is 6808bp. Phylogenetic analysis of the nucleotide of ORF2 showed that this strain is more close to Japanese strain (AB000285). Using RT-PCR, 566 samples from children with diarrhea in shanghai were screened and the results showed that infection average rate of HAstV is 7.59% and main infection strain is HAstV-1. |