The Impact Of Risk Factors Of Functional Dyspepsia On Symptoms And Prognosis

BackgroundThere are a few reports about functional dyspepsia(FD)risk factor, which focused more on the overall disease risk factors than risk factors on the symptoms,and less reports about affect of prognosis of risk factors。Our research focused on FD-related risk factor in the impact on the symptoms and prognosis。MethodOur surveyed 130 cases of out-patients which meet the Rome III criteria,examinated excluded stomach organic disease and other visceral organ involvement by endoscopic and ultrasonography and reflux disease。Conditions to receive FD questionnaire。By logistic regression models examine the related risk factors and follow-up one year, observed the outcome。ResultsAdjusting for gender , the OR(odds ratio)= 2.77 and 3.09 in postprandial fullness and early satiety,but there are 0.48 and 0.54 in epigastric pain and epigastric burning respectively。Adjusting for age,OR= 1.02 in epigastric pain,but 0.95,0.98 and 0.96 in postprandial fullness,early satiety and epigastric burning respectively。Adjusting for smoking, OR=0.10,0.52 in epigastric pain and epigastric burning respectively。Adjusting for dringking,OR=1.01 in epigastric pain,but 0.22,0.22,0.77 in postprandial fullness,early satiety,and epigastric burning respectively。Adjusting for HP.(Helicobacter pylori)Infection,OR=0.66,0.66,0.93 and 0.71 in postprandial fullness,early satiety,epigastric pain,epigastric burning respectively。Adjusting for life satisfaction,OR=1.88,3.41 in early satiety,epigastric pain respectively,but 0.49 in epigastric burning。Adjusting for mood swings,OR=1.01,1.30 and 1.04 in postprandial fullness,epigastric pain and epigastric burning respectively,while 0.69 in early satiety。Adjusting for education,OR=1.38,1.69 and 1.12 in postprandial fullness,early satiety and epigastric burning respectively,while 0.83 in epigastric pain。In the distribution of symptoms of risk factors, early satiety is more susceptible in higher education,P=0.028,and there is greater probability of epigastric pain in mood swings,P=0.004。Follow-up one year,there are no significant difference in the distribution of postprandial fullness,early satiety,epigastric pain,epigastric burning。There are no significant difference of initial symptom scores of classification risk factors,P>0.05。After one year,overall symptom scores was significantly lower than initial, P=0.006;and symptoms score of male is significantly lower than female, P=0.000。ConclusionFemale is a risk factor of postprandial fullness and early satiety。Older and drinking are risk factors of epigastric pain。There are no difference in HP. infection in the postprandial fullness, early satiety, epigastric pain and epigastric burning。Low life satisfaction is a risk factor of early satiety, epigastric pain。Mood swings is a risk factor of postprandial fullness,epigastric pain and epigastric burning。Higher education is a risk factor of postprandial fullness,early satiety and epigastric burning。In the distribution of symptoms of risk factors:early satiety is more likey in higher education,and there is greater probability of epigastric pain in mood swings。There are a better outcome of FD,and the outcome of male is better than female。...