Analysis Of Pathogens Distribution And Drug Resistance In Lower Respiratory Tract Infection Among Aged People

Objective: To analyze the pathogens distribution and drug resistance in senile patients with lower respiratory tract infection.Methods:Bacteria culture and drug sensitivity test of 1097 cases of senile lower respiratory tract infection,2993 sputum samples from Sep 2006 to Sep 2009 were analyzed retrospectively.Results: A total of 1696 strains of bacteria were separated,it included 1390 (82%) strains of Gram—negative bacilli,composed by pseudomonas aeruginosa,Escherichia coli,Klebsiella pneumoniae mainly.The ESBLs positive rates of Escherichiacoli,Klebsiella pneumoniae were 71.7%and 55.9%respectively.There were 52 strains (3%)among which the Staphyloccocus aureus Rosenbach and coagulative ferment negative staphylococci were the predominant.There were 254(15%) strains of fungi among which the candida albicans was the most predominant.The result of drug sensitivity test showed that there were high rates of drug resistance in most bacteria strains,but there were different drug resistance rates to different anti-bacteria agents.Conclusion: The Gram-negative bacilli are the major pathogens isolated from senile patients with lower respiratory tract infection.The emergence of drug resistance is a serious problem and the result of drug sensitivity test are significant to select proper anti-bacteria agents.