The Clinical Research Of Qiling Tongfeng Decoctionon On Gouty Nephropathy

Objective: to physicians embalmed in generalization of gouty nephropathy based on knowledge, from clinical perspective Qi spirit gouty nephropathy gout decoction in the treatment of curative effect, and discusses its mechanism, for clinical treatment gouty nephropathy looking for Chinese medicine treatment.Methods: 60 patients with gouty nephropathy patients were randomly divided into two groups: treatment group, 30 cases in 30 patients. The treatment group named again received allopurinol piece treatment on the basis of, again be flavored treatment group 3 to general party received allopurinol piece treatment. Observe three treatments (12 weeks), observe two groups before and after the treatment clinical symptoms, signs, blood, urine PH value, acid 24-hour urine protein quantitative and routine blood, kidney merit, the blood fat, yellow purine oxidase, serum type IV collagen changes.Results: the total effective rate of 90 in treatment group and control the total effective rate was 65.6﹪, with significant differences between the two groups (P < 0.05). The treatment group in improve symptoms, signs, reduce the 24-hour urinary protein quantitative, improve renal aspects of reactive, lipid than in control group (P < 0.05).Each group were significantly lower blood levels of serum uric acid, but significant differences between (P > 0.05). The treatment group and control group after treatment, the yellow purine oxidase level is before treatment are decreased obviously (P < 0.05). The treatment group can effectively reduce serum type IV collagen level, before and after the treatment was significant difference (P < 0.05), obviously better than the control group.Conclusion:Qi spirit gout decoction n the treatment of pixu renal weak, wet hot and humid stasis gouty nephropathy turbid type has good curative effect, can effectively improve patients' symptoms and signs; Reduce 24-hour urinary protein quantitative, lipid improve renal work; Inhibit yellow purine oxidase activity, reducing patients serum type IV collagen level. 3 that flavored gouty nephropathy general square treatment has good curative effect, effectively formula for clinical treatment.