Anaplastic Oliodendroglioma With Drop Metastasis To The Spinal Cord And Review Of The Literature

Objectives:The aim of this study was to increase understanding about metastasis to spinal cord from intracranial oligodendroglial tumorsBackgroud:Although metastatic inolvement via diffuse CSF spread of primary central nervous system (CNS) tumours is more likely in premitive neuroectodermal tumours. Metastatic involvement of the cerebro-spinal fluid (CSF) pathway in oligodendrogliomas is not uncommon; however, symptomatic involvement of the spinal cord is very rare, cases of drop metastasis to spinal cord by intracranial oligodendroglial tumors have only been rarely described.Methods:We reported a 56-year-old woman who developed diffuse spinal metastases 9 months after a left temporal lobe anaplastic oligodendroglioma to discuus the mechanism. The patient after sugery failed to accept the chemotherapy and radiotherapy, about nine months after MRI demonstrated metastastic to the spinal cord, eleven months later transferred to the cerebellum.Significanc: This case adds to the few cases of spinal metastasis from intracranial ODGs.To the best of our knowledge, this represents the 19th recorded case in the literature. Also, it is the first case of incranial oligodendroglial metastases to the spinal cord and producing symptoms in China.