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Clinical Effect Evaluation Of Treating Ankylosing Spondylitis With Bo's Abdominal Acupuncture Combined With Drug

Posted on:2012-09-30Degree:MasterType:Thesis
Country:ChinaCandidate:G H ChenFull Text:PDF
GTID:2154330335967925Subject:Orthopedics scientific
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BackgroundAnkylosing spondylitis (ankylosing spondylitis, AS) is a chronic inflammatory disease of unknown cause, which mainly violates axial skeleton. It is characterized by sacroiliitis and disease attached. Although most of ankylosing spondylitis will not pose a serious threat to the human life, it brings great suffering to patients, and severe affection of the life quality of patients because of the stiffness, pain, and even spinal rigidity, deformity occurring in the waist and back. It makes serious body dysfunction. There is no satisfactory way to cure this disease completely which is internationally recognized as a refractory disease.This paper reviewed the cause of Traditional Chinese and Western medicine in understanding AS, summing up the knowledge and research of the etiological factor, pathogenesis, diagnosis and mechanism of drug action. It also generalized the current treatment of AS and discussed the theory evidence of abdominal acupuncture in healing it. Through the analysis of the control experiment, abdominal acupuncture on the clinical effect of AS was evaluated. And I will propose my views and opinions on abdominal acupuncture for future clinical studies of AS in the following passages.ObjectiveThrough observing the comparison of clinic efficacy of two methods of treating ankylosing spondylitis with oral administration of sulfasalazine tablets, diclofenac sodium sustained-release tablets and abdominal acupuncture combined with oral administration of sulfasalazine tablets, diclofenac sodium tablets, and applying a number of quantizational index to evaluate the curative effect of the two ways mentioned above, this subject aimed to provide literature and data support to establish an efficacy evaluation system and further help the research of the future use of abdominal acupuncture treatment on AS.Research and MethodsAmong the outpatients and inpatients in Zhuhai Branch of Guangdong Provincial Traditional Chinese Medical Hospital,40 cases were selected who were in accord with the inclusion criteria and were divided randomly into two groups with 19 cases in acupuncture combined with drug group and 21 cases in drug group. Drug group were treated with sustained release tablets of diclofenac sodium 75mg, one time per day; sulfasalazine 0.5g per time and 3 times per day for the 1st week,0.75g per time and 3 times per day for the 2nd week,1.0g per time and 3 times per day for the 3rd week and the next three monthsthird week each oral 1.0g, three times a day, to maintain the end of therapy to three monthsthird week each oral 1.0g, three times a day, to maintain the end of therapy to three months until the therapy ends. Acupuncture combined with drug group were treated with Bo's abdominal acupuncture as well as tablets. Basic regimen:Zhongwan (D), Xiawan (D), Qihai (D), Guanyuan(D), Zhongji (D), Qixue (D),Daheng double (M), Wailing double (M), Huaroumen double(M). Pain in the lower lumbar and sacral vertebrae:added Guanyuanshang or Guanyuanxia according to the relevant parts. Pain in the hip:added Xiafengshinei (M). When necessary, treated with point-selection partly at the same time. The manipulation was of light stimulation but heavy and tense, without tingling and painful sensation. Needles were kept for 20-30 minutes and transferred after 10 minutes each time. After consecutive treatment of 6 days every week from Monday to Saturday for 3 months, the course of treatment finished. The main effect indicators used in the two groups included pain score, ESR, HSCRP, IgA, IgG, IgM levels, finger-ground distance, chest stretching distance and the time for 20m walking distance. The relevant data were selected into the database so as to establish a database system. And the statistical analysis software was used to come up with a conclusion.ResultsThe data of this study showed that:after the abdominal acupuncture combined with drug treatment for 3 months, the related symptoms, signs and indicators of AS, such as pain score, ESR, HSCRP, IgA, IgG, IgM levels, finger-ground distance, chest stretching distance and the time for 20m walking distance have been improved visibly. From the.indicators of pain score, ESR, IgA levels, finger-ground distance, chest stretching distance and the time for 20m walking distance, we can see that abdominal acupuncture combined with drug treatment has better effect than drug treatment. The significant difference of clinical effect between abdominal acupuncture combined with drug treatment and drug treatment alone was statistically significant.ConclusionBo's Abdominal Acupuncture combined with oral administration of sulfasalazine, diclofenac sodium sustained-release tablets in the treatment of ankylosing spondylitis can get a good effect.
Keywords/Search Tags:Ankylosing spondylitis, Abdominal acupuncture, Effect evaluation
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