The Clinical Analysis Of Radiofrequency Catheter Ablation Of Paroxysmal Atrial Fibrillation

Objective The status of research methods were used with self-questionnaire, S-F36 to evaluate Health Questionnaire survey of quality of life of patients before and after clinical treatment and changes in heart function and influencing factors; factors of atrial fibrillation recurrence after radiofrequency ablation, to further improve the the indication for radiofrequency ablation of atrial fibrillation. The study aimed to improve the success rate of radiofrequency ablation of atrial fibrillation.Methods Selected from September 2008 to October 2010 in Kunming Medical College of Cardiology, First affiliated Hospital,35 atrial fibrillation patients with radiofrequency ablation were followed up. The general information, ECG, ultrasound, etc.of radiofrequency ablation in patients with atrial fibrillation before are collected, while quality of life of patients before assessed with application of SF-36 scale. Preoperative three-dimensional guidance were used to guide circumferential pulmonary vein ablation. ECG, ultrasound, surgical recurrence, etc. will be collected after 6 months radiofrequency ablation of paroxysmal atrial fibrillation and SF-36 scale will be applicated for re-assessment of postoperative quality of life. This study is comparison of preoperative and postoperative quality of life; improvement of cardiac function; recurrence factors.Results1 Quality of life35 cases of radiofrequency ablation of paroxysmal atrial fibrillation, the results of 70 questionnaires were analyzed using paired t test analysis. All dimensions of quality of life before and after surgery in the comparison were significantly different, except Body Pain (t=1.559, P=0.125)(see Table 7).2 Analysis of cardiac functionBy ultrasound examination, in the patients with paroxysmal atrial fibrillation cardiac function(LVEF) before and after radiofrequency catheter ablation, the difference was significant in cardiac function(LVEF) of patients with paroxysmal atrial fibrillation before and after radiofrequency catheter ablation. (t=-4.718, P <0.001(see Table 5)3 Factors Affecting the Quality of LifeUsing multiple linear regression analysis, it was demonstrated that improvement of patients quality of life after radiofrequency ablation of atrial fibrillation is negatively correlated to abnormal blood lipids, positively correlated to ejection fraction improvement and no recurrence, meaning that quality of life is improved better with normal blood lipids after ablation compared to abnormal; the better quality of life improved with no recurrence after radiofrequency ablation of atrial fibrillation recurrence compared to recurrence; the more of ejection fraction improvement after radiofrequency catheter ablation, the better quality of life of patients (see Table 8,9).4 AF recurrence factors after radiofrequency ablationUsing univariate analysis showed that age (z=-2.025, P=0.043),p-wave dispersion (r=2.193, P=0.033),hypertension (χ2=6.286, P=0.012) and LAD are significant. Using logistic regression analysis showed that age,hypertension and LAD are signifiant (see Table 10,11,12).5 Clinical observationSinus bradycardia were showed in two patients after radiofrequency ablation of paroxysmal atrial fibrillation.Conclusion1. There are restored sinus rhythm and improved cardiac function and improved quality of life by circumferential pulmonary vein isolation of treatment of patients with paroxysmal atrial fibrillation;2. Age, hypertension, left atrial inner diameter are the impact factors for recurrence of atrial fibrillation after radiofrequency ablation;3. Sick sinus syndrome (slow-fast type) is ill-suited for radiofrequency ablation.