Aids Spread In The Families And Its Influence Factors

ObjectivesTo understand HIV infection in Shandong province spread within families and the impact, by comparing different types of People who live with HIV/AIDS(PLWHA) with the attitude and behavior changes of their spouses and the spread of mother to child transmission. Analysis the impacts to the second generation of the family about Knowledge on AIDS, condom use, features of different groups, and whether different groups of people informed the spouse test results and other factors on the spread of AIDS, in order to provide a scientific basis of HIV/AIDS further control.MethodsAIDS epidemic in Shandong Province is analyzed including the survival data of married HIV infected persons and AIDS patients of relevant information, based on 17 cities in Shandong Province from 1992 to 2009 are found in the survival of AIDS and their spouses for the survey. These couples can all participate in the survey-based study. All the HIV infected persons and their spouses have their HIV antibody tested in six months and the positive HIV infection caught meet diagnostic criteria; Follow-up data integrity, informed consent, correctly understand and answer the questionnaire. Questionnaire, including "AIDS infection spread within the family questionnaire," "spread of AIDS infection within the family questionnaire negative spouse." Meanwhile reports of epidemic diseases of mother-to-child transmission cases and positive maternal seeding drug blocking mother-to-child transmission situation were surveyed, EpiData3.1 was used, the data was detected based on logic and parallel double-entry. After verification application SPSS 17.0 statistical analysis software were used for analysis. ResultsAs of December 31, 2009, 1757 cases of PLWHA were found in Shandong Province, of which 447 cases of death, 1310 cases alive. We investigated all the 1310 cases that have their and their spouses and children's'HIV antibody tested in six months (infants need to wait until 18 months old to run their HIV antibody testing). 213 PLWHA families have been investigated in our survey, 102 couples are both HIV antibody positive and 111 are single positive. There are 315 cases are PLWHA and 111 negative spouses, and 124 cases are women of childbearing age.1. Demographic characteristics of HIV infected / AIDS patients within the familyIn 213 families of HIV infection, mainly the Han nationality, a total of 359 persons (accounting for 84.27%), 67 ethnic minority people (accounting for 15.73%);Based education to middle school or below, 58 of them illiterate people (accounting for 13.62%), 149 primary schools (accounting for 34.98%), junior 162 (accounting for 38.01%), more than 57 high schools (accounting for 13.38%).Aged between 23 to 69 years, mainly 30 to 50 years old, with 289 people, accounting for 67.84% (289/426). The longest time of Husband and wife living together was 12 years, the shortest 6 months, the average 2.67 years.2. HIV infected / AIDS patients spread of husband and wifeIn the survey of 213 families living with HIV, 111 spouses of the family are HIV antibody negative, the rest couples (102 families) are both HIV antibody positive. In the 102 households, the number of one spouse who has been confirmed of HIV infection right after the other was diagnosed as positive is 96 and persons have been infected by their spouses are 6. Sexual transmission rate between spouses was 5.13% (6/117). In three families, the spouses are infected after their spouses'positive test results have been informed, and their sexual transmission rate between spouses is 2.94% (3/102). The rest families of the 6 have been infected in the absence of positive test results information, and the sexual transmission rate between spouses is 20.00% (3/15). After analyzed the influence of sexual transmission between couples informed and failed to inform the spouse of the test results, we concluded the RR is 6.80. The risk of HIV transmission between spouses of failing to inform the spouse test results is 6.80 times to those informed families. 3. HIV infection / AIDS patients transmission between couplesIn 213 families, 102 persons who infected HIV transmitted to their spouses, in which 7 people living with HIV are blood-selling history of the couple, 3 couples with HIV have extramarital sexual history, 2 couples living with HIV information available can not determine. At last, 90 families were conformed to infecting HIV,111 families not, AIDS spreading total rate of patients transmission was 44.78% (90/201). In 201 families, the men first infected were 75, 21 transmitting to the women, the ratio for 28.00%; the women first infected were 75, 21 transmitting to the men, the ratio for 54.76%. There were significant differences (χ~2= 13.62, P < 0.05) between couples who were both positive and not.In 90 HIV families which were both positive, there were 80 families had definitive infected time. In which 44 were infected Within a year , accounting for 55.00%, 64 were infected (including 1 year) within 3 years, accounting for 80%.4. HIV infection / AIDS Knowledge about AIDS patientsThe rate of AIDS occurred between husband and wife couple Knowledge about AIDS was 64.44% (116/180), compared to 65.77% without any communication between husband and wife couples (146/222), Results revealed there is no difference (χ~2= 0.02, P >0.05). From a gender perspective, there is statistical difference (t′= 3.28, P>0.05) between men and women full awareness of knowledge. AIDS knowledge among men was better than women.5. HIV/AIDS patients infected status in foreign women, blood donorsIn 201 families, there were 89 foreign women, in which 49 were both positive couples, spreading rate of foreign women was 55.06%(49/89), 112 local women, in which 41 were both positive couples, spreading rate of local women was 36.6%(41/112). Foreign women couples spread risk was higher than local women (χ~2= 6.83, P < 0.05). There were 30 blood donors, in which 14 families were positive , comparing to 16 who were not, the spreading rate was 46.67% (14/30). There was no significant difference between foreign women and blood donors in HIV transmission (χ~2= 0.63, P > 0.05).6. HIV infection / AIDS situation of the patient mother to child transmissionUntill December 31, 2009, Shandong Province, a total of 1757 cases were reported, of which 643 cases were women, women of childbearing age (15 to 49 years old) 551 cases, the number of women of childbearing age accounted for 85.69% of women. A total of 65 cases of mother to child transmission were reported, accounting for 3.70%.Of 65 cases of mother-to-child transmission cases, 61 cases were detected in Shandong province, other provinces reported 4 cases.56 children were reported in childbearing women, 17 children were infected, the rate of mother-to-child was 30.36%(17/56).In 54 children, 44 were not implemented drug block , the natural rate of mother-to-child was 38.64%(17/44). 44 children were implemented drug block, none of them infected.7. Influence factors of HIV infected / AIDS patients within couplesCondom use (χ~2=10.06, P <0.05), foreign women(χ~2=6.83, P <0.05), whether to inform their spouses testing result (RR=6.80)were influence factors of HIV transmission between couples.Conclusion1. Shandong HIV/AIDS patients marital spreading rate is relative higher than other provinces. Occurrence of AIDS transmission between husband and wife focused on living together within three years.2. Promptly informing their spouses testing results can change their related behaviors, improve condom use and also are main infection factors of HIV transmission in families.3. Foreign women marital spread rate is higher than the local women, Looking birth as the mainly purpose, failing to use condom continues which can prevent the spread of AIDS effectively is the primary reason contributing to spread of HIV in couples.4. Drugs block contained an effective method of vertical transmission, we should continue to increase the scope of drug blocked.