Comparative Efficacy Between Radio Frequency Ablation And Surgica Resection For Small Primary Liver Carcinoma

Objective:To compare the clinical effect of radiofrequency ablation and surgical resection for small primary liver carcinoma.Methods:84 patients with small primary liver carcinoma whose tumor diameter≤5cm were recruited during Feb.2004 to May.2010 in the Affiliated Tumor Hospital of Guangxi Medical University, in which 40 cases were treated by radiofrequency ablation and other 44 cases were after surgery. Multivariate statistics was performed to analyze clinical data and follow-up results in order to provide useful references for the treatment of small primary liver carcinoma in clinical practice.Results:1. The results of radiofrequency ablation group were as follows:complete clearance ratio was 87.50%, the incidence of complications was 10.00%, recurernce and metastasis rate was 75.00%. The results for operation group were as follows:complete clearance ratio was 100%, the incidence of complications was 15.91%, recurernce and metastasis rate was 63.64%.There was great statistical significance (p=0.02)between the two groups in the complete clearance ratio of tumor, in contrast there was no statistical significance in terms of complication rate, recurernce and metastasis rate as well as disease free survival.2. Radio frequency ablation group and operation group:1,3,5- disease free survival were 85.00%,37.50%,25.06%and88.59%,50.0%,31.78% respectively. Mean survival time was 30.08 months and 32.76 months, which shows no cumulative survival differences between the two groups.Two sub-groups were divided according to the tumor diameter:one was≤3cm group,1,3,5- disease free survival for radioreequency ablation group and operation were 85.72%,47.58%,33.33%and87.46%,62.50%,43.78%, Mean survival time was 39.43 months and 38.97 months. there was no cumulative survival differences between the two groups.3cm