Study On Correlation Between TCM Syndrome Type And T Lymphocyte Subpopulation In Patients With Chronic Hepatitis B

Objective: It is to explore the correlation between chinese medcine syndrome of chronic hepatitis B and T lymphocyte subpopulation.Methods: 150 patients with chronic hepatitis B were diagnosed with differential chinese medcine syndrome, such as stagnation of liver-energy and asthenia of spleen, middle-stagnation of wetness-heat, blood stasis obstruction of collaterals,deficiency of liver-Yin and kidney-Yin,deficiency of spleen and kidney Yang, and their T lymphocyte subpopulation were determined.By analyzing of the research data, to explore the correlation between chinese medcine syndrome of chronic hepatitis B and T lymphocyte subpopulation.Results: Patients with T-lymphocyte subsets (CD₃⁺,CD₄⁺,CD₈⁺,CD₄⁺/ CD₈⁺)levels were significantly different (P<0.01):1.Chronic hepatitis B patients with peripheral T lymphocyte subsets and normal people to change significantly, CD₄⁺ down, CD₈⁺ increased, CD₄⁺/CD₈⁺ decreased (P<0.001), but no significant change in CD₃⁺(P>0.05).2.Different Syndromes T-lymphocyte subsets changed significantly by F and q test, liver stagnation and spleen deficiency→dampness-heat accumulation→blood-stasis in meridian→liver-kidney yin defieieney→spleen-kidney yang deficiency, CD₄⁺/CD₈⁺ decreased gradually .In the liver stagnation and spleen deficiency syndrome of damp heat in the resistance,CD₄⁺/CD₈⁺ although lower, but not upside down,but later the permit blood stasis,CD₄⁺/CD₈⁺ inversion and gradually increased.Conclusion : 1.Chronic hepatitis B patients with peripheral T lymphocyte subsets and normal people to change significantly, CD₄⁺ down, CD₈⁺ increased,CD₄⁺/CD₈⁺ decreased.2. Chronic hepatitis B chinese type of certificate of lymphocytes and other t change with the kidney, liver, and the strengthening of the false evidence in the most significant reduction CD₄⁺/CD₈⁺.