Survey And Analysis Of Cognitive Function Of Outpatients In Neurology Clinic In Chinese Northeast Region

Objective:To investigate the incidence,the dangerous factors and the characteristics of every kind of cognitive impairment in Neurology Clinic in Chinese Northeast Region.Methods:The outpatients who can satisfy our limited standard were selected in Neurology Clinic in The First Hospital of Ji Lin University from September to November in 2009,and were conducted Mini-Mental State Examination (MMSE). The score of them who were illiterate(Who did never receive education)is less than or equal nineteen,the score of them who only received primary school education(the years of education were less than or equal six)is less than or equal twenty-two,the score of them who were secondary level and above(the years of education were greater than or equal six)is less than or equal twenty-six。Those who can satisfy our limited score would accept the formal investigation,including their massage of general demographic data , the complaints and symptoms of cognitive impairment,the physical examination and a series of neurologic psychological assessments. At the same time,they conducted CT or MRI of the head.In the end,we got the consistent diagnosis of the disease by more than two experienced neurological physician.Results:The patients classified as mild cognitive impairment were 0.40% of the screened patients,and amomg them MCI-A were 0.12%,MCI-V were 0.15%,Mixing MCI were 0.03%. The patients classified as dementia were 0.22%,and among them the Alzheimer,s disease(AD) were 0.06%,vascular dementia(VD) were 0.11 %,the mixing dementia were 0.02%. The patients classified as normal individuals were 0.05%。In addition,0.17% of the screened patients was composed of other kinds of cognitive impairment.The score of immediate memory repetition of famales is higher than that of males;With the age growing,the score of delayed recall test decreases obviously. With educational attainments enhancing, the score of MMSE increases obviously.The score of immediate recall test,delayed recall test,long-delayed recall test in MCI-A and AD is much lower than that in MCI-V and VD. The score of ADL in AD is much higher than that in VD. The score of NPI in MCI-A and AD is much higher than that in MCI-V and VD. The score of CDR in AD is much higher than that in VD.The above differences were with satistically significant.The score of Hamilton Depression Scale of MCI-A and AD and that of MCI-V and VD has no significant difference.Conclusion:The incidence of MCI-V and VD surpass the incidence of MCI-A and AD in Chinese Northeast Region. The detetion rate of MCI of Famales is higher than that of males.the detetion rate of dementia increases gradually with age. the detetion rate of MCI increases obviously before seventy-five years old,in patients above seventy-five years old,decreases obviously compared to the others.The score of immediate recall repetition test of Famales is much higher than that of males. With the age growing,the score of delayed recall test decreases obviously. With educational attainments enhancing, The score of MMSE increases obviously. The score of immediate recall repetition test,delayed recall test,long-delayed recall test in MCI-A and AD is much lower than that in MCI-V and VD.It suggests that the memory decline in MCI-A and AD is more prominent. The score of ADL in AD is much higher than that in VD. It suggests that the independence in activity of daily life of AD is worse. The score of NPI in MCI-A and AD is much higher than that in MCI-V and VD.It shows that the neuropsychiatric symptoms of MCI-A and AD is more prominent.The score of CDR of AD is more higher than that of VD.It may caused by its memory decline, the decline of independence in activity of daily life and serious neuropsychiatric symptoms. The score of Hamilton Depression Scale of MCI-A and AD and that of MCI-V and VD has no significant difference.