| HBV infection is a serious public health problem. Chronic hepatitis B is one of the most frequent chronic infectious diseases, which mainly involves liver. The hepatic cirrhosis and liver cancer caused by chronic hepatitis B bring about a heavy economic burden to the nation and individual personal. Due to the specificity of the occupation, medical staff, as a high risk group, have a high risk to infect HBV. Hepatitis B vaccine inoculation is the most effective method to prevent HBV infection.'The research on whether or not it is necessary for our medical staff to reinforce or reinoculate hepatitis B vaccine' is the item of prevent medical unit.It shows that HBV infection is a serious public health problem. It has a bad influence to public health.Object:To find out the distributed condition and the influencing factors about the hepatitis B marker of the medical staff. To comprehend the situation about the hepatitis B vaccine injection of the medical personnel. To investigate whether or not it is necessary for our medical staff to reinforce or reinoculate hepatitis B vaccine. To grasp the perception about the hepatitis B knowledge of the medical staff. To provide basis for preventing hepatitis B in effect and formulating corresponding safeguard.Methods:We extract three hospitals of different sizes randomly. we collect blood serum sample of the medical staff coming from the above three hospitals, then the serological markers of hepatitis B (HBsAg, anti-HBs and anti-HBc) are detected with the i2000 corpuscule ELISA kit produced by Abbott Laboratories through hepatitis reagent research center of Beijing university. We also make a questionnaire survey of the medical staff in order to analyze the distributed condition and the influencing factors about the serological markers of hepatitis B. There are 2265 questionnaire surveys in total, including 52 cases of HBsAg positive and 2213 cases of HBsAg negative. We use SPSS 13.0 software for statistical analysis. The differences of positive rate among all groups are analyzed by chi-square test.Results:The survey shows:The positive rate of HBsAg is 1.92% in three hospitals; anti-HBs positive rate is 63.18%; the singular anti-HBc positive rate is 5.32%; The negative rate of HBsAg, anti-HBs and anti-HBc is 29.84%. In three hospitals, there is no significant difference in the positive rate of HBsAg (P> 0.05); the positive rate of anti-HBs is differenct(P<0.05). There is significant difference between A and B (P<0.05); The singular anti-HBc positive rate is differenct(P<0.05). There is significant difference between A and B as well as A and C (P<0.05); the negative rate of HBsAg, anti-HBs and anti-HBc is different (P<0.05), there is significant difference between A and B as well as A and C (P<0.05).The rate of HBV infection is 47.33% in medical staff. While the highest rate of HBV infection was A, the lowest rate of HBV infection was C. The rate of HBV infection is different(P<0.05); there is significant difference between A and C(P<0.05); the highest rate of HBV infection is the age of 40 to 49 years, the lowest rate of HBV infection is the age of 20 to 29 years, the rate of HBV infection increases with the increasing of age. In groups of subjects age, there is significant difference between the age of 20 to 29 years and the age of 40 to 49 years (P<0.05); the highest rate of HBV infection is nurse,and then doctor and other staff. In groups of subjects occupations, there is significant difference between nurse and other staff (P<0.05); the infection rate of HBV of vaccination history, invasive medical history, hairdressing history is higher than no-vaccination history,no-invasive medical history, no-hairdressing history, and there is significant difference (P<0.05);The survey shows that:the positive rate of HBsAg is the highest in the group of 40 to 49 years, and the lowest in the group of 20 to 29 years; 61.54% of the medical staff have needle stabbing injuries,98% of them can deal with needle stabbing injuries correctly; this disease has an influence on routine work and life more or less; the staff of HBV have some psychological problems, such as anxiety fear and so on. The staff of HBV can not give the total correct answers for the knowledge of HBV infection prevention and treatment. The survey of the negative of HBsAg shows:39.95% of the medical staff have the history of hepatitis B vaccination,90.6% of the medical staff deem that it is necessary to take the vaccination; 92.99% of the medical staff can accept and complete the process of free charge vaccination; the medical staff can not give the total correct answers of hepatitis B basic knowledge, transmission, prevention and treatment; 77.51% of the medical staff are interested in the knowledge of prevention and treatment of hepatitis B.Conclusion:(1) It is necessary for medical staff to strengthen or re-vaccinated hepatitis B vaccine.(2) Increasing investment in prevention to improve vaccination coverage is necessary.(3) HBV infection is relevant to the age, occupation, vaccination history, history of invasive treatment and hairdressing hisrory in medical staff.(4) It is necessary to strengthen the publicity of hepatitis B prevention and control knowledge; and to improve the awareness of hepatitis B prevention to medical staff(5) It is necessary to strengthen occupational education in medical staff. At the same time, enhance the prevention and self-protection awareness.
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