Serum Retinol Binding Protein 4 Levels And The Relationship Between Fetal Growth And Development

AbstractBy testing different gestational age, birth weight infants in different serum retinol binding protein 4 levels and insulin levels of serum RBP-4 in fetal growth and development, nutrition may play a role in metabolism and the possible mechanism for the evaluation of intrauterine development of new indicatorsMethodSelect Shanxi Province from March to May 2010 Department of Neonatology Children's Hospital a total of 89 patients hospitalized newborns, according to the relationship between birth weight and gestational age were divided into 3 groups, 30 cases of small for gestational age(SGA) children, 30 cases of appropriate for gestational age(AGA)children, 29 cases of large for gestational age(LGA)children, were mild inhalation and ingestion of amniotic fluid syndrome in children.。Collected within 24 hours after birth, the femoral vein 5ml, detected by ELISA in 89 cases of neonatal serum RBP-4 and INS levels, and detailed records of their birth weight, birth weight according to intrauterine nutritional status assessment, Application SPSS17 .0 software for statistical analysis to p<0.05 was considered statistically significant.Results1,Full-term newborns SGA, AGA, LGA 3 serum RBP-4 levels were significantly different, AGA serum RBP-4 levels higher than the SGA group, LGA serum RBP-4 levels higher than the AGA group.2,Full-term newborns SGA, AGA, LGA 3 serum INS levels were significantly different, AGA serum INS levels higher than the SGA group, LGA serum INS levels than AGA group.3,Serum RBP-4 levels and neonatal birth weight was significantly positively correlated.4,Serum INS levels and neonatal birth weight was significantly positively correlated.5,Serum RBP-4 full-term newborns and INS levels were significantly correlatedConclutionRBP-4 involved in the regulation of fetal growth and development, which may be by influencing INS levels, and intrauterine regulate the growth and development.