The Effects Of Orthodontic Force On IL-8 And SICAM-1 Level In The Fluid Around Micro-implant Anchorage

Objective:Deviding the patients with implant anchorage into stable group and unstable group according to the stability of implant anchorage after loading orthodontic force .To investigate the change of IL-8 and sICAM-1 in the fluid around micro-implant anchorage,analyze the factors affecting implant anchorage's stability.Method: The 40 implant anchorage from 20 patients were divided into stable and unstable group by the situation after loading orthodontic force.The fluid was collected before and 1,2,3 months after orthodontic force around implant anchorage. IL-8 and sICAM-1 levels were analyzed using ELISA, and data analysis was performed using SPSS17.0 software package. Results: Significant difference (P<0.05) was shown in the indexes (the fluid volume around implant anchorage,IL-8 and sICAM-1 levels) between stable group and unstable group. It seems that the fluid volume around implant anchorage,IL-8 and sICAM-1 levels in unstable group express more than that in stable group. And also significant difference (P<0.05) was found in unstable implant anchorage during different loading time, the fluid volume around implant anchorage,IL-8 and sICAM-1 levels express more and more along with the expansion of loading time.Conclusion: The increase of the fluid around implant anchorage,IL-8 and sICAM-1 level in unstable implant anchorage group may be correlated with inflammation's intensification, the level of IL-8 and sICAM-1 can reflect the stability of implant anchorage effectively.