Research Of Left Ventricular Function Before And After Transcatheter Closure In Patients With Pda By Echocardiography

Objective The aim of this study was to observe the changes of left ventricular function in patients of PDA pre-operation and post-operation treated by transcatheter closure using occluder by RT-3DE and TDI,and to evaluate whether left ventricular function was influenced by the change of blood volume.In addition,the accuracy of different methods in evaluating the left ventricular function were estimated.Methods LVMI,Tei index,LVEDVI and LVEF were evaluated in 36 patients with PDA who were successfully treated by transcatheter closure using occluder before and after the intervention. Additionally,LVMI,Tei index,LVEDVI and LVEF were evaluated in 36 health volunteers.Results 1,Before operation,Tei index of patients with PDA were less than the health volunteers,LVMI and LVEDVI were more than the health volunteers,and the differences were statistically significant(P<0.05). 2,After intervention,Tei index of patients with PDA were more than before,LVMI and LVEDVI were less than before,and the differences were statistically significant (P<0.05). Tei index and LVEDVI measured by RT-3DE were significant different at different time (within 3 days,the first month,the third month and the sixth month) after the closure (P<0.05). The change of LVMI obtained by RT-3DE is not dramatically different at different time (within 3 days,the first month,the third month and the sixth month) after the closure (P>0.05). The change of LVEF obtained by RT-3DE before and after intervention is not significant at different time after the intervention (P>0.05). 3,LVMI of patients with PDA evaluated by RT-3DE had a close correlation with LVEDVI evaluated by RT-3DE(r=0.529,P<0.01);Tei index of patients with PDA had a close correlation with LVEDVI evaluated by RT-3DE(r=-0.161,P<0.05).4,LVMI,LVEDVI and LVEF evaluated by ME are statistically different with them evaluated by RT-3DE (P<0.05).Conclusion After intervention,blood volume of left ventricular decreased. LVMI and Tei index could be influenced by the change of left ventricular blood volume. LVMI estimated by RT-3DE and Tei index estimated by TDI were both able to accurately reflect left ventricular function. They played a significant part in estimating therapeutic effect in patients with PDA after transcatheter closure.