Quantitative Analysis Based On The Relationship Between The Symptoms And The Syndrome Elements Of Prescription And Syndrome

Ob j ect i ves:In the work we aimed at applying the latent semantic analysis to investigate the correlation between the symptoms and the syndrome elements of blood stasis symptoms based on the available clinical case records database. We also intend to summarize the syndrome elements that are related to blood stasis symptoms, as well as the symptoms displayed in blood stasis.Approaches:(l)Based on theories and prevailing clinical standard operation procedures in Traditional Chinese Medicine, we standardized the available data and tabulated them in the categories of the symptom standards, the basic symptoms, and the syndrome elements-symptom relevancy coefficient, respectively; (2) We also proved the feasibility of our approach by randomly taking 183 formula indications from the textbook of Traditional Chinese Medical Colleges, Formula Indications (7th Edition), quantitatively analyzing and verifying the correlation between the symptoms and the syndrome elements therein using latent semantic analysis; (3) We further collected and tabulated the clinical data on blood stasis symptoms, quantitatively investigated the correlation between displayed symptoms and the syndrome elements, identified 3 syndrome elements with the largest relevancy coefficients; (4) We finally introduced the accuracy test and the completeness test as two sets of criteria, and combined them with theories and knowledge in Traditional Chinese Medicine to analyze and evaluate our research results.Resu I ts:(1) Using the approach of latent semantic analysis we investigated the 3 syndrome elements with the largest relevancy coefficients in the data table, and compared them with the syndromes obtained using Chinese keywords classifications. It shows that the average degree of accuracy was about 71.8%, and the average degree of completeness was about 65.3%. (2) Through the analysis on the blood stasis symptoms related syndrome elements we identified the key displayed clinical symptoms when complication took place in blood stasis syndrome element and other related ones. (3) We also discovered some potential syndrome elements, which has broadened the symptoms-related clinical applications.