The Applied Study Of Youshengning No.3 In Threated Abortion

Objective: The threatened abortion a commonly seen gynecological and obstetric disease, may develop into miscarriagy in most cases. Doctor practice western medicines mainly by hormone supplement therapy.The curative effect is affirmed , but it may cause the female embryo male gender. Youshengning No.3 is the Heilongjiang Province nation woman grade old doctor of traditional Chinese medicine Ma Baozhang tablet after the proven prescription. After 20 remaining years of life's clinical uses, discovered after the treatment, has made the remarkable clinical progress. To explore Youshengning No.3 treating the threatened abortion side of the mechanism, this issue by the parties to observe the clinical for 120 threatened abortion kidney patients or type of the analysis and animals of the model Progesterone, Estradiol,β-subunit chorionic gondaotropin and Prolactin level of the uterus and ovaries organization of and to keep yo upregnant role, to study medicine, for further research Youshengning No.3 treating the threatened abortion had to be the treatment provided in accordance with the experiment.Methods: 120 patients who measure up to the standards, randomly divided into treatment group ( Youshengning No.3 with Subunit chorionic gondaotropin group) and control group( Subunit chorionic gondaotropin group) on two groups of the patient's age, the week, abortion, and hospital treatment for days, the process of analysis and observations on treatment in chinese medicine for the improvement of the situation warrants, serum and the promotion ofβ-subunit chorionic gondaotropin and Progesterone changes. Fills in the pregnancy 10th day for the big mouse takes Mifepristone medicine 3.75mg/kg, establishes the Wister mouses threatened abortion model.In the pregnancy 12th day, after big mouse eye socket draws blood, after cervical vertebra dislocation execution, the dissection takes the womb and the ovary, carries on the immunohisto-chemistry. Uses the emission immunization to examine the blood progesterone (P), estradiol (E2),β- subunit chorionic gonadotropin (β-HCG) and the prolactin (PRL) four kind of hormones the content.Result: Treatment group, 62 patients, heal 17, 38 effectie, 7 failed, efficient 88.71% ; 58 patients of control group , heal 12 , 31 effectie, 15 failed , efficient 74.14% . The level ofβ-subunit chorionic gondaotropin and Progesterone of 120 patients increase significantly after treatment. With respect to blood of Progesterone Estradiolβ-subunit chorionic gondaotropin and Prolactin , the study showed that: (1)there was significant difference between the model group and the natural pregnancy group (p<0.01);(2) there was no difference between the progestin group and the natural pregnancy group(p>0.05);(3)there was significant difference between the high dosage group of Youshengning No.3 and the progestin group (p<0.01);(4) there was no difference between the progestin group and the medium dosage group of Youshengning No.3 (p>0.05).Conclusion: Youshengning No.3 had regulatory effect in the content of blood progesterone, subunit chorionic gondaotropin , and in the prevention of threatened abortion.