| Introduction Children with cerebral palsy (cerebral palsy, CP) was reported firstly by William John Little in 1862, and it is also known as Little disease.It means non-progressive brain damage and the syndrome of developmental defects from the moment of conception to infancy.It manifests as movement disorders and abnormal posture ,accompanied with mental retardation, convulsions, hearing and visual impairment, abnormal behavior,etc.It was basically cause of one of the major diseases with physical disabilities following the poliomyelitis of children controlled in china. Now, with the constant improvement of the health care system, obstetrical and neonatal intensive care of perinatal medicine, including the continuous improvement, perinatal mortality was declined, but survival often appear cerebral palsy, resulting in the incidence of cerebral palsy steadily increased. WHO reported the incidence of cerebral palsy was 1‰~5‰, and Prevalent survey in six provinces in China showed it was 1.12‰~2.17‰.Cerebral palsy's cause has complexity and diversity. Currently, the main cause in cerebral palsy are neonatal asphyxia/hypoxic-ischemic encephalopathy,nuclear jaundice,persistent jaundice, premature birth/low birth weight children, intrauterine infection, cerebral infarction and so on. New studies suggest that genetic factors, congenital intrauterine infection, levels of inflammation gene and immunity damnification factors are a potential factor in the incidence of cerebral palsy, and asphyxia, hypoxia, premature birth, and jaundice are the triggering factors.The most common type is spastic, followed by mixed, dyskinetic, tonic, ataxic, hypotonic and so on. Spastic by paralysis of parts are divided into Monoplegia, Diplegia, Triplegia, Hemiplegia, and Guadriplegia. Most of cerebral palsy is associated with varying degrees of cranial CT, MRI imaging changes, but the skull imaging is not a basis for diagnosis of cerebral palsy.At present, the cure for cerebral palsy very difficult, no cure for cerebral palsy of the effects of drugs yet. Once cerebral palsy is diagnosed, the remedy of becoming integrated of physical exercise is adopted. At present, Bobath therapy is the most widely used in the international community.Now,Conductive Education is one of the most effective ways as the treatment of children with cerebral palsy.It maximize the mobilization of the potential of voluntary movement of the children. It stimulate the children's interest and active participation in awareness entertain by amusement ,rhythmics and intention.It focuses on the comprehensive rehabilitation of children with cerebral palsy, making them "perfect" posture full development. The combination of collective training, rehabilitation training and home-based rehabilitation are its preponderance.Cerebral palsy not only brings children and their parent great pain, but also increases a heavy burden in the family and community. With the implementation of family planning system, and socio-demographic of the aging, it is recognized that cerebral palsy is a re-emphasis and further understanding of diseases. Therefore, understanding the cause of cerebral palsy, supplementary examination, complications, efficacy and relevance of the different clinical classifications help to prevent the incidence, reduce the incidence, diagnose early, choose effective rehabilitation treatment, reduce disability rates and improve the quality of the children's live.Objective: It provides a scientific frame of reference for the prevention and treatment of cerebral palsy by collecting and analyzing information on a complete medical history of cerebral palsy children, exploring the etiology, laboratory examinations, complications, efficacy and the pertinence of different clinical classifications.Method: To study clinic information of children with cerebral palsy collected in our hospital rehabilitation center in 2006 ~ 2008. 394 cases information of children with cerebral palsy of treatment selection for the first time are a swatch of study in analysing of causes, complications and laboratory examinations. The first stay 372 children with cerebral palsy were randomdly administered with conductive education combined Bobath therapy (study group) or Bobath therapy (control group),and GMFM-88 was used to assessed before and after treatment.Analysis of efficacy, will be the first treatment of 372 children with cerebral palsy in accordance with the treatment methods (parents in the case of a voluntary informed choice of treatment method) divided into two groups of different principles: Use of Conductive Education + Bobath combined treatment for cerebral palsy patients Conductived+Bobath children as a group, select the same year, a comprehensive patient education, using only Bobath therapy in children with cerebral palsy as the Bobath group.Results:1. There are 316 cases younger than 3 years of age in 394 cases, which percent is 80.2%.The percent of Spastic is 76.2%. It proves the age correlates to clinical classification.2. The percent of 294 cases of Spastic is 74.6%.That of 55 cases of Hypotonic is 14.0%.That of 32 cases of Mixed is 8.1%.That of 12 cases of Dyskinetic is 3.1%.That of 1 cases of Ataxia is 0.3%. The Spastic's is highest , and the Ataxia's is lowest.3. Clinical Classification and Causes3.1 Single-factor analysis: There are 13 factors such as placental dysfunction, inappropriate medication during pregnancy, exposure to toxic substances during pregnancy, threatened abortion, bleeding during pregnancy, pregnancy cholestasis, quantity of amniotic fluid,premature, birth weight, childbirth by surgery, asphyxia and hypoxic ischemic encephalopathy, head injury and jaundice are related to the clinical classification of cerebral palsy (P<0.05).3.2. Multi-factor analysis: The results showes premature is related to hypotonic and mixed (P>0.05), bleeding during pregnancy, asphyxia, childbirth by surgery and inappropriate medication during pregnancy are related to hypotonic(P>0.05), exposure to toxic substances during pregnancy, quantity of amniotic fluid jaundice are related to mixed(P> 0.05).4. Assistant examination: Abnormal rate of CT/MRI, EEG were no significant difference in clinical classification of cerebral palsy (P> 0.05).5. Complication associating with the clinical types: There is a significant difference in hearing impairment, rickets, patent foramen ovale in different clinical classification of cerebral palsy (P <0.05). Language barriers, mental retardation, epilepsy, poor eyesight, small head deformities, emotional and behavioral disorders, iron deficiency Anemia in the type of cerebral palsy are no significant difference in different clinical classifications of cerebral palsy (P> 0.05).6. Clinical classification and efficacy Study group and control group after treatment have a significant efficacy.The efficacy of the forester is better than the later in 3 -year-old group in Spastic (P <0.05).7. Conductive education combined Bobath therapy is more effective than solo Bobath therapy.Conclusion:1. The percent of spastic is highest in clinical classification, followed by atonic, mixed, dyskinetic and ataxia.And the age of children with cerebral palsy is ofen less then 3 years.2. Clinical classification of cerebral palsy are associated with placental dysfunction, inappropriate medication during pregnancy, exposure to toxic substances during pregnancy, threatened abortion, bleeding during pregnancy, pregnancy cholestasis, quantity of amniotic fluid, premature, birth weight, childbirth by surgery, asphyxia and hypoxic ischemic encephalopathy, head injury and jaundice.3. Premature is related to hypotonic and mixed, bleeding during pregnancy, asphyxia, childbirth by surgery and inappropriate medication during pregnancy are related to hypotonic, exposure to toxic substances during pregnancy, quantity of amniotic fluid jaundice are related to mixed.4. Hearing impairment, rickets, and patent foramen ovale are relevant to different clinical classification of cerebral palsy.5. Both therapy could improve gross motor function of children with cerebral palsy, and conductive education combined Bobath therapy is more effective than solo Bobath therapy.
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