Analysis And Application Value Of TCT Detection In Screening Incervical Disease

Objective 1.based on the results of thinprep cytology test (TCT) as the positive starting point, evaluate the validity and reliability of TCT To investigate the reasonable positive point in the diagnosis of cervical dysplasia.2.Investigate the application value of TCT in the screening of cervical dysplasia through researching the distributed character of TCT in different age And different clinical characteristic.Methods 1 From March to November 2009,271 women had TCT and cervix living tissue detection.Regard pathology detection result as golden standard, based on the detection result of ASCUS,ASC-H,LSIL and HSIL which worked as the positive starting point respectively, elvaluate the realitility and validity of TCT in cervical dysplasia.. And by drawing ROC curve, discuss the next reasonable positive starting point of TCT in cervical dysplasia.2 From March of 2009 to Augst of 2009,1578 women had TCT. By analyzing the result distribution of TCT at different age, whether have bleeding after sexual intercourse ectopy on clinic, whether have columnar ectopy in gynecology examination, discuss the application value of TCT in the cervical dysplasia.Result 1.Set the differient positive point for the examination result of TCT, use the examination result of pathology as golden standard to evaluate the the validity and reliability, get the result:the diagnosis level of TCT incervical disease is higher. The corresponding point of ASC-H as positive point is most close to the top left corner of the graph, which means choose this point as critical value of cervical dysplasia, both missed diagnosis and misdiagnose are lower. indicate the consistency of hight.of TCT and pathology examination. 2 Through statistic analysis of the 1578 women who had TCT, the distribution of the value of ASCUS, ASC-H, LSIL, and HSIL is different in differient ages. The inflammation inspect of bleeding after sexual intercourse is lower than no bleeding after sexual intercourse,The rate of ASCUS,ASC-H. LSIL,HSIL,is higher than no bleeding after sexual intercourse. The differience of TCT and extend of columnar ectopy is not meaningful for statistics.Conclusionl ASC-H is the most reasonable positive point in diagnosing CIN.for the women no bleeding after sexual intercourse,and ASCUS is the most reasonable positive point in diagnosing CIN.for the women bleeding after sexual intercourse.2 In the practise of clinic, those women who are at the age of 30-35,45-60 and have the history of bleeding after sexual incourse should be paid more attention to do screening of CIN.