Bronchial Arterial Chemoembolization Combined With Argon-helium Cryosurgical Ablation For Treatment Of Non-small Cell Lung Cancer

Objective Using prospective and retrospective research method, the study had a deep and particular research into curative effect on 22 non-small cell lung cancer (NSCLC) patients who had been treated by a therapeutic alliance, bronchial arterial chemoembolization (BACE) combined with argon-helium cryosurgical ablation. The result can offer some help with the clinic applications of the therapeutic alliance. The study tries to find out the virtues and complications of the therapeutic alliance. According to the result, it is possible for us to enhance the efficacy and enlarge the therapy methods of NSCLC.Methods Using prospective and retrospective research method, we select 22 NSCLC patients who had been treated by BACE combined with argon-helium cryosurgical ablation during Jun 2008 to Sep 2009. The size of tumor, extent of necrosis, complications and quality of life will be analyzed.Results1,The evaluation of CTâ‘ CT monitoring immediately after surgery22 NSCLCs underwent argon-helium cryosurgical ablation after (BACE). Contrast material-enhanced CT was performed immediately after the surgery, 1 month,3 month, and then every 6 months after treatment to evaluate the response to therapy. Complete necrosis was attained in 13 (59%) of 22 lesions; partial necrosis in the remaining 9 (41%) lesion.â‘¡Curative effect evaluationAccording to the WHO standard, the treatmen is divided into complete response, partial response, stable response and progressive response.2 karnofsky performance status (KPS) and quality of lifeKPS of patients with complete necrosis was significantly better than that of patients with partial necrosis after treatment.3 Complications Embolization toxicity of BACE in this group accords to NCI-CTC. Patients' toxicity effects in this group after the treatment mainly for non-infectious fever, cough, sputum, a transient increase in serum phosphate, fatigue and cough, expectoration, fever, and myoglobinuria, all improved after treatment.Conclusions1 The therapeutic alliance had true curative effect. It has the importance of improving quality of life and enlarging extent of tumor.2 BACE combined argon-helium cryosurgical ablation is effective on remarkable dispersion, symptom easing without severe side effects.3 The association of BACE and argon-helium cryosurgical ablation is worth delivering widely as a new project of NSCLC treatment.