| Objective To compare outcomes in wavefront-guided LASIK(WASCA) to corneal topography-guided LASIK (TOSCA) in treating myopia.Methods A randomized, prospective study of 69 myopic eyes of 38 patients undergoing either WASCA or TOSCA with the MEL80 excimer laser system was performed.33 eyes of 17 patients with RMS≥0.4μm were performed WASCA, and 36 eyes of 21 patients with RMS<0.4μm were performed TOSCA. Higher order aberrations (HOAs), contrast sensitivity, corneal topography, best spectacle-corrected visual acuity(BSCVA) and uncorrected vision acuity(UCV), were measured and recorded pre-operatively and at two weeks, one month and three months post-operatively for each eye.Results There is no significant difference of spherical power, cylinder power, spherical equivalent and age between two groups pre-operative(P>0.05).TOSCA group presents smaller mean Spherical equivalent than WASCA group(P<0.05).RMS, spherical aberration,CIM,SF all increase in both groups after operation. At 3 months, there was no significant difference of RMS value increase(RMS),CIM,SF between groups. Mean spherical aberration increase(Z(4,0)) of WASCA group is 0.50±0.26; while the (Z(4,0)) of TOSCA group is 0.72±0.39, there is statistical significance (P<0.05) between 2 groups. TOSCA group performs better Contrast sensitivity without glare in 1.0 c/d,1.7 c/d,2.6 c/d,4.2 c/d and 10.4 c/d than WASCA group 3 months after operation(P<0.05).Conclusions WASCA results in better spherical aberration, while TOSCA results in better BSCVA,better contrast sensitivity and less corneal irregularity in three months post-operative. TOSCA is more efficient than WASCA in treating myopia. |
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