| Background:Heart failure and atrial fibrillation are common cardiovascular disease associated with quality of life. They often coexist and for each can result in the other, and create a vicious circle.Object:To assess the benefit between catheter ablation of rhythm control and drugs of heart rate control strategy in patients with heart failure (HF) who had atrial fibrillation (AF).Methods:We studied 28 consecutive patients with HF and AF from June 2006 to February 2009 in our center, as a rhythm control group, who were undergoing catheter ablation for AF. We selected as controls 28 consecutive patients with HF who were undergoing drugs of heart rate control and oral anticoagulant therapy for AF, matched according to age, sex, classification of AF, heart function, left atrial dimension (LAD), left ventricular end-diastolic dimension (LVEDD) and left ventricular ejection fraction (LVEF).Results:During 17±9 months follow-up, there was one person in rhythm control group died from HF, as compared with none in the heart rate control group (P=1.000). 68%(19) of patients were free of AF post of catheter ablation. The rhythm control approach compared with the heart rate control strategy was associated with a significantly morbidity of stroke events (0 vs.22%, P=0.023), hospitalization rate (1.2±0.5 vs.1.8±1.0, P=0.005), improved heart function (61%vs.29%, P=0.031), decreased LAD (64%vs.22%, P=0.003) and LEDD (46%vs.4%, P＜0.001), and increased LVEF (78%vs.46%, P=0.026).Conclusion:Ablation of rhythm control was superior to drugs of heart rate control in patients with heart failure who had atrial fibrillation.
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