Efficacy Analysis Of Laparoscopic Adrenalectomy Treatment Of The Aldosterone-producing Adenomas

Objective:Explore the clinical effect of Laparoscopic adrenalectomy treatment of the Aldosterone-producing adenomas to provide guidance for clinical therapy and improve disease diagnosis and treatment.Methods:Select 72 cases of Aldosterone-producing adenomas which is confirmed by clinical symptom and pathology. All patients were under general anesthesia transperitoneal laparoscopic adrenalectomy. Analyse the preoperative clinical, surgical treatment and postoperative clinical data of efficacy to obtain the clinical treatment effect.Results:1.The all of 72 patients were successfully treated by laparoscopic adrenalectomy. No intraoperative conversion to open cases, no intraoperative blood transfusion case, no case of postoperative complications. The average operation time was 52.8±39.7min, the average blood loss was 63.8±37.3ml, all the patients within 72 hours after restoration of gastrointestinal function, the average hospital stay after surgery was 5.77±0.78day. Cases were pathologically diagnosed adrenal adenoma, the average maximum diameter of adenoma was 2.14±0.63cm.2. Preoperative the headache and dizziness symptom improvement rate was 95.52%, the fatigue symptoms improvement rate was 93.75%, the Polyuria, nocturia and polydipsia symptoms improvement rate was 100%, the Symptom of intermittent limb weakness improvement rate was 100%, the Symptom of periodic paralysis improvement rate was 100%. 3. All the patients'serum potassium level and serum aldosterone level were return to normal range.4. ALL 72 patients were hypertensions.44 patients after surgery to restore blood pressure to normal levels,28 patients after surgery were still higher than normal blood pressure or need to take antihypertensive medications. According to the Postoperative patients with normal blood pressure and sustained hypertension into two groups, the two groups were found in sex, with or without family history of hypertension, polyps, adenoma size, preoperative systolic blood pressure, diastolic blood pressure before surgery, preoperative serum potassium, plasma aldosterone before surgery in these areas were not significantly different. However, in age, time and duration of hypertension on the blood pressure spironolactone treatment response of these three areas were significantly different.Conclusion:Laparoscopic adrenalectomy treatment of the Aldosterone-producing adenomas is one ideal way. The efficacy of surgery is significant. However, older patients with hypertension, the duration and preoperative spironolactone poor response to antihypertensive treatment affecting the patient's blood pressure returned to normal levels of significant factors.