| PurposeCommand explicitly the incidence and clinical features (2001-2009) 65 cases of bronchioloalveolar carcinoma in General Hospital of Guangzhou MilitaryMethodRetrospective analysis of 2001-2009, Guangzhou General Hospital of Guangzhou Military Region were 775 cases of lung cancer, according to WHO histological classification of lung cancer in 2004 standards committee of non small cell lung cancer is divided into adenocarcinoma, squamous cell carcinoma, BAC, large cell lung cancer, other types of NSCLC lung cancer (adeno carcinoma, carcinoid, etc.). Case through the systematic collection of electronic patient's age, sex, length of stay, surgical, pathological diagnosis, cough, weight loss patient information, and smoking, drinking and other related factors, statistical analysis, the number of confirmed cases of lung cancer patients of changes in and mainly for adenocarcinoma, squamous cell carcinoma, bronchioloalveolar carcinoma in 3 groups, will be collected to the clinical symptoms, influencing factors, clinical stage information and data into comparative analysis between groups.ResultThe number of confirmed cases of lung cancer,34 cases in 2001 rose to 148 cases in 2009, significantly increased with time trend; squamous cell carcinoma accounts for lung cancer increased from 41.1% in 2001 to 16.9% in 2009, cancer accounted for lung cancer increased from 28% in 2001 increased to 67.6% in 2009 was significantly increased trend of significant changes with time (x2=55.888, P<0.05); big, small cell lung cancer was no significant change with time, representing a ratio of 3.1 of lung cancer%,3.2%. Were included in BAC 65 cases, accounting for lung ca-ncer, adenocarcinoma of the percentage of 8.39%, respectively,14.8%, no signify cant changes with time (P> 0.05),2001-2009 BAC cases diagnosed each year the number of 2 to 13 cases. BAC 32 cases of female patients, accounting for 49.2% BAC percentage. Squamous cell carcinoma and other NSCLC the proportion of women was 18.95% and 33.22%, with statistical significance (P<0.05). To cough, hemoptysis, weight loss, chest pain, as a general physical examination found six clinical manifestations of lung adeno, squamous cell carcinoma, BAC statistical analysis among the three groups were significantly different (x2=33.81, P <0.01), respectively, cough, cough blood, weight loss, chest pain, physical examination found that among the three groups of five to conduct statistical analysis, including cough and the other two groups were significantly different (x2=20.576, P<0.01), physical examination findings and the other two groups were significantly different (x2=19.787, P= 0.007), BAC 15% of clinical manifestations of cough, chest pain 15%, hemoptysis 11%,29% weight loss, physical examination found that 30%. IA, IB BAC percentage of patients was 56.6%, while the gland, squamous cell carcinoma were 15.0%,16,66%, suggesting that BAC patients diagnosed with early o'clock, glandular, squamous cell carcinoma, it is in advanced cases. BAC patients diagnosed when the average age of 59.21 years, women's average age was 57.23 years,60.94 years for men, lung cancer, the average age of 59.23 years, lung cancer, the average age of 60.56 years, compared among the three groups No statistically significant (P> 0.05).65-70 age group is the peak incidence of BAC, while the peak age of onset in the 50-55 female age group. Cancer, NSCLC, BAC in accordance with the median age group for statistical analysis, in which cancer of men and women (<60 years age group) differences (x2=139.9, P<0.01), suggest adenocarcinoma were young women sick trend. Gland, squamous cell carcinoma, BAC proportion of smoking patients:53.4% squamous cell carcinoma, adenocarcinoma 49.1%, BAC 23.0%, BAC and the other two groups were significantly different (x2=20.4, P<0.01).ConclusionThe incidence of BAC has increased over time, BAC accounted for lung cancer, adenocarcinoma of the percentage of cases no significant change with time, and lung cancer, lung cancer showed significantly increased trend also see significant changes over time. The incidence of BAC compared with other NSCLC women have high incidence of atypical clinical features. BAC patients showed more weight loss, cough, chest pain is the most physical examination was found in patients with BAC. BAC over time for early diagnosed cases of lung adenocarcinoma, squamous cell carcinoma, it is in advanced cases. BAC age of onset lung cancer and other types of young age, no significant trend similar to adenocarcinoma of sick women were getting younger and younger, BAC peak age of onset is 65-70 years age group, while women peak in the 50-55 age of onset age group, BAC young patients in the proportion of female patients than male patients. BAC percentage of smoking patients with adenocarcinoma, squamous cell carcinoma compared to 30% lower, indicating bronchioloalveolar carcinoma relative lung carcinoma weak relationship with smoking, smoking is associated with the BAC is needed further verification.
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