A Clinical Analysis Of Periventricular-intraventricular Hemorrhage In Premature Infants

Objective:To explorer the incidence, risk factors, clinical manifestations of Periventricular-intraventricular hemorrhage (PVH-ⅣH) in premature infants.Methods:Three hundreds and fifty-eight premature infants (gestational age< 37 weeks) admitted to the Affiliated Children's Hospital,Zhejiang University School of Medicine from January 1st,2009 to December 31st,2009 were enrolled in this retrospective study. The clinical date include birth weight, gestational age, gender, lmin Apgar score, obstetric history, cranial ultrasound results were collected and analyzed. Use the multivariate logistic regression model to analyze the risk factors of PVH-IVH in the premature Infants whose gestational age≤34 weeks.Results:The incidence of PVH-IVH and high-grade PVH-IVH are 24.0%(86/358) and 1.9%(7/358). In the multivariate logistic regression model, birth weight, lmin Apgar score and mechanical ventilation are the risk factors of PVH-IVH in the premature infants (gestational age< 34 weeks).Conclusions:Periventricular-intraventricular hemorrhage is a common complication of premature Infants. Cranial ultrasound plays an important role in diagnosis. In the premature Infants whose gestational age< 34 weeks, birth weight, asphyxia and mechanical ventilation sustained the association with a greater risk of PVH-IVH. Prevention of associated risk factors may reduce the incidence of PVH-IVH.