Comparison Of Different Treatments For Extraction Sockets On The Effect Of Regeneration Of Alveolar Bone

In oral clinical, in order to restore patient's mastication function and obtain better long-term effects of restoration, we need to extract some loose tooth. The artificial denture will not be repaired until the alveolar ridge absorption change stably, only then carries on. In the early wound healing, if a tooth extraction stimulated by external factors, wound healing even will be delayed. After tooth extraction, pressure to stop bleeding is commonly used in clinical, suture or packing iodoform gelatin sponge is always used for impacted tooth extraction. At present, nano-HA filling after tooth extraction is used increasely. Suture, packing iodoform gelatin sponge, filling the hydroxyapatite can play a better part on closing extraction and preventing complications, but the comparing of these different ways on regeneration of alveolar bone has not been reported currently.Objectives: To compare the effect of the three treatments with that of pressure to stop bleeding on the promotion of early healing of extraction socket and preventing the alveolar ridge from atrophy after extraction; To compare the effect of sutures and iodoform gelatin sponge with that of nano-HA on the promotion of early healing of extraction socket and preventing the alveolar ridge from atrophy after extraction.Methods: Each dog will be extracted bilateral the third lower incisor, the first and third premolars. All the teeth were extracted with the same ways. The right side was kept vacant after teeth extraction as the control group, the other side was dealt with three different methods as experimental side: implanting nano-HA artificial bone, suture and iodoform gelatin sponge. 1, 2, 4, 8, 12, 24 weeks later, the animals were killed. The specimens were examined by digital X-ray, light microscope. Results: 1. There were significantly different between each different method and compression to stop bleeding on preventing the absorption of alveolar bone and new bone formation (P<0.05).2. Three experimental groups:â‘ On preventing absorption of alveolar bone: There was significantly different between nano-HA group and other experimental groups(suture group and iodoform gelatin sponge group) (P<0.05);There was also different between the suture group and iodoform gelatin sponge group(P<0.05).â‘¡On bone density: There was significantly different between the nano-HA group and suture group(P<0.05); There was significant difference between the nano-HA group and iodoform gelatin sponge group(P<0.05); There was no difference between the suture group and iodoform gelatin sponge group(P>0.05).â‘¢In the promotion of new bone formation: There was significantly different between the nano-HA group and suture group (P<0.05); There was significantly different between the nano-HA group and iodoform gelatin sponge group(P<0.05); There was no difference between the suture group and iodoform gelatin sponge group (P>0.05).Conclusions: 1: The three methods can reduce the wound area of contacting with the outside world, prevent the entry of foreign matter effectively, in order to form a clot with better quality. It is helpful for the early healing of tooth extraction and reducing the absorption of alveolar ridge.2: On the effects of the early healing and preventing absorption of alveolar bone, suture and iodoform gelatin sponge were better than compression to stop bleeding, but worse than nano-hydroxyapatite.3. The effect after a tooth extraction from good to poor: filling nano-HA,iodoform gelatin sponge, suture, oppression simply to stop bleeding.