| Objective:To observe the efficacy, safety and stability of ciliary groove Implantable Collamer Lens(ICL) implantation for the treatment of cataract.Methods: To choose 20 cases of cataract patients (30 eyes), aged 57-75 years old, average age (66.32±8.15)years, who comes to our hospital for treatment from March 2008 to June 2008. They were randomly divided into ICL implantation (experimental group), IOL implantation group (control group), 15 eyes in each group. Every case in the experimental group was used surface anesthesia then give 3.2mm clear corneal incision phacoemulsification before intraocular lens (ICL, V3-type, Switzerland Staar Surgical-AG Corporation) were implanted into ciliary groove; Every case in control group was used the surface anesthesia then give 3.2mm clear corneal incision phacoemulsification before IOL (Intraocular lens, IOL, Staar Japan Corporation) into the capsular bag; then to observe intraocular pressure of the experimental group and control group after operation 1day, 1week, 2weeks, 1month, 2months and 3months; To observe the experimental group and control group after operation 3months , including their uncorrected visual acuity, best corrected visual acuity, corneal endothelial cell count, two sets of slit lamp microscopy of pigmented intraocular lens surface and posterior capsular opacification, the ultrasound biomicroscope (UBM) the location of measurement, such as intraocular lens.Results: All patients had uncorrected visual acuity improved after 3 months.The mean uncorrected visual acuity was (0.79±0.22), the mean best corrected visual acuity was (0.97±0.12) at 3months after the operation in the experimental group,there is apparently difference between postoperative and preoperative in the exerimental group (P <0.05); The mean uncorrected visual acuity was (0.81±0.14), the mean best corrected visual acuity was (0.89±0.25) at 3months after the operation in the control group,there is apparently difference between postoperative and preoperative in the control group (P<0.05).The difference between the mean best corrected visual acuity of the two groups was not significant (P>0.05) at 3months after the operation.The effectively spherical equivalent refraction in the experimental group was (-2.85±1.25)D;the effectively spherical equivalent refraction in the control group was (-2.25±1.45)D,there is no difference between the two groups was significant (P>0.05). Postoperative intraocular pressure: the experimental group after 1day, 1week, 2weeks, 1month, 2months, 3months IOP on average was (18.01±2.31) mmHg, (17.10±2.40)mmHg,(16.52±2.68)mmHg,(14.32±1.87)mmHg,(16.22±1.09)mmHg,(14.83±2.34)mmHg; the control group after 1day, 1week, 2weeks, 1month, 2months, 3months,for the average IOP (17.61±3.40) mmHg, (15.63±1.98)mmHg,(17.24±1.57)mmHg,(15.10±3.01)mmHg,(15.53±1.42)mmHg,(16.42±2.01)mmHg;the experimental group in each of the different postoperative time points compared with the preoperative intraocular pressure is not significant difference (P>0.05); the control group at different postoperative at each time point compared with the preoperative intraocular pressure is not significant difference (P>0.05); the difference between the intraocular pressure of the experimental group and control group at different time points is not significant (P>0.05). The mean endothelial cell count was (2611.45±146.32) / mm2 at 3 months after the operation in the experimental group; the mean endothelial cell count was (2645.82±156.21) / mm2 at 3 months after the operation in the control group; postoperative intraocular pressure changes in endothelial cell count difference between the two groups was not significant (P>0.05). Intraocular lens surface of the incidence of pigmentation of the experimental group was 46.6% (7 / 15), while the control group was 6.6% (1 / 15), the difference was significant (P <0.05). There was no significant difference between postoperative and posterior capsular opacification (P>0.05). after 3months, UBM showed the postoperative corneal endothelial surface of the centre and the ICL before the average distance between(2.32±0.12)mm in experimental group, while the corneal endothelium after the central government and the IOL anterior surface of the average distance about(3.74±0.51)mm in control group, the difference in the experimental group was significant (P<0.05); while the difference in control group was significant (P<0.05); there was significant difference between the experimental group with the control group (P<0.05). In experimental group, 15 eyes ICL trench four loops in the ciliary fixed; 15 control group eyes IOL in the capsular bag. There was no infection case in the two groups of postoperative intraocular postoperative complications.Conclusion: 1.Implantable collamer lens implantation appears to be an effective,safe and reliable method for the cataract treatment.2. Ciliary groove implantation of ICL is a kind of the cataract treatment with safety, effectiveness and stability after operation 3 months follow-up period; However, its long-term effects need further observation.
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