The Genetic Polymorphism Of 4 Mini Y-STR Locus In Han Population In The North Of China

ObjectiveMake use of the primer of new design,we designed proptosis to aim at 4 locus DYS522,DYS508 of the mini Y-STRs,the mini Y-STR of the DYS632 and DYS556 locus.Carrying on an examination to 224 samples of Liaoning Chinese's crowd is a forensic medicine personal identification and parents and children authenticate to provide a data.Materials and methodsRandom abstraction have no consanguinity relation of 224 Liaoning Chinese male individual haematoporphyrin kind,use a normal regulations method to carry on abstraction,primer design and PCR to expand to the DNA,appliance ABI 3100-Avant gene analysis instrument(Applied Biosystems),to the mini Y-STR locus DYS522, DYS508,DYS632 and DYS556 carries on an examination.ResultThrough the DYS522,DYS508,the mini Y-STR locus of DYS632 and DYS556 carries on an examination.DYS522 sites examine proptosis 5 discrimination power(DP) with personal allele,allelomorph to 0.6495,the excluding probability of paternit(EPP) is;DYS508 sites examine proptosis 6 discrimination power(DP) with personal allele, allelomorph to 0.7006,the excluding probability of paternit(EPP) is;DYS632 sites examine proptosis 3 discrimination power(DP) with personal allele,allelomorph to 0.5224,the excluding probability of paternit(EPP) is;DYS556 sites examine proptosis 6 discrimination power(DP) with personal allele,allelomorph to 0.7454,the excluding probability of paternit(EPP) is.ConclusionsThe 4 mini Y-STR locus has better genetic polymorphism in Chinese Chinese group in the north and the availability authenticates at forensic medicine personal identification and parents and children.