Clinical Research Of The Agent Of Invigorating Spleen Dissipating Blood Stasis And Detoxicating Combined Chemotherapy In Patients Of Carcinoma Of Stomach

This study Led by the traditional Chinese Medical,combining the clinical practice has established the principal treatment,which covers nourishing qi to invigorate spleen, activating blood circulation to dissipate blood stasis,detoxicating to anticancer,has put forward the principal pathogenesis of the patients on advanced stage,which is the weakness of the spleen and stomach,toxicities tying with blood stasis. We take the of invigorating the spleen,dissipating blood stasis and detoxicating as the fundamental method, which is a part of treatment experience of professor Ruiping Wang,to treat the advanced stage patients.Objective:Aim to evaluate the therapeutic effect and safety,by the way of assessing the size of the tumor,symptom,the quality of life,energy,tumor marks and the side-effect of the chemotherapy,of the principle of invigorating the spleen,dissipating blood stasis and detoxicating when encountering the patients.Methods:The 40 definite patients of carcinoma of the stomach have been assigned into two groups randomly,20 in the test group,17 in the control group(3 shed).Patients in the test group receive the combined therapy,which contain the agent of invigorating the spleen, dissipating blood stasis and detoxicating and FOLFOX proposal. The chemotherapy has carried out for 2 periods,8 weeks in all. The agent consists of Huangqi,Dangshen,Baizhu, Huaishanyao, Yiyiren, Fuling,Erzhu,Xianhecao,Shuyangquan,Longkui. One potion a day, decocted to 300ML, 150ML one time,8 weeks in succession. The control group receive the same medicine,the same dose but agent.Result:It has significant difference between the two groups on ameliorating symptom, increasing the quality of life,relief nausea and vomiting of the toxic and subsidiary action of chemotherapy medicine (P<0.05) .Conclusion:It is feasible and rational that agent of invigorating the spleen,dissipating blood stasis and detoxicating should be adopted to treat patients of carcinoma of stomach on advance stage. And it would provide a more effective treatment, a foundation of further developing anticancer Chinese drugs pharmaceutics.