Schisandra Extract Serum Lipid Research

This article was to study the hypolipidemic effect of Schisandra extraction. Schisandra were crude extracted with 75% ethanol firstly. The ethanol extract diluted with water, and shaken with ethylacetate and N-butanol. Solvents were distilled to produce ethylacetate, and N-butanol fractions. Hyperlipomia model was ICR mice. They were divided into negative and positive group, N-butanol high-dose group, N-butanol low-dose group, ethylacetate high-dose group and ethylacetate low dose. Normal saline, Zhimaikang Jiaonang 5.15 mg/ml, Schisandra N-butanol extraction 10 mg/ml, Schisandra N-butanol extraction 5 mg/ml, Schisandra ethylacetate extraction 8 mg/ml, Schisandra ethylacetate extraction 4 mg/ml were administered orally for five days and the bloods were collected through the eyes for testingTC, TG, HDL-C, and LDL-C.The datas were analysed by SPSS13.0, The conclusion was 10 mg/ml of Schisandra N-butanol extraction had hypolipidemic effect in the respect of reducing TG and TC.