Endometriosis In Adolescence: With An Analysis Of 27 Cases

BackgroundEndometriosis(EMs) is a disorder in which abnormal growths of tissue, histologically resembling the endometrium, are present in location other than the utering lining. EMs is a frequently disease in women in reproductive age, pelvic pain and infertility are the cardinal symptoms. The disease stage is classified I ~ IV according to the revised American Fertility Society(AFS). The aims of treatments are attempt to eliminate the endometriotic tissue, relieve the pelvic pain, ameliorate infertility, decrease recurrence of EMs. Treatment options should be dictated by paitient's status, surgical therapy is the first treatment of choice, drug treatment is the subsidiary choice. Adolescent endometriosis is attached little importance. This investigate explore the clinical feature, diagnosis and management of endometriosis in adolescence.Material and MethodsTwenty seven cases of adolescent EMs with surgical treatment were selected, which were admitted during 2003.7 and 2008.8 in Women's Hospital School of Medicine Zhejiang University for a retrospective study. The cases are analyzed to explore the clinical feature, pathogenesis, diagnosis and management of endometriosis in adolescence.ResultsThe mean age of the 9 cases with anomalies of female reproductive system was (13.56±2.75),and that of the 18 cases without anomalies of female reproductive system was (17.17±1.95), with significant difference between them ( P＜0.05 ) . The percentage of those patient with durations of flow is longer than 7 days was (61.54%,16/26), with dysmenorrhea was (62.96%,17/27), with body mass index lower than 18 was (29.6%,8/27) and with setum CA125 level more than 35 KU/L was (68%,17/25). The main symptom leading to the visit was dysmenorrhea. 16 cases without anomalies of female reproductive system had undergone laparoscopy, and 2 had undergone laparotomy for acute pelvic pain. 4 cases with anomalies of female reproductive system undergone laparotomy and remove the obstructive anomalies at the same time, and 5 had undergone operation on vagina and laparoscopy. 15 cases received medical therapy after surgery.ConclusionsAdolescent EMs often accompanied with genital tract anomalies, and the main symptoms are dysmenorrhea. Lower BMI and longer durations of flow are maybe the risk factors of Adolescent EMs. Surgery and pathology should be undertaken to make a definitive diagnosis. Medical therapy after surgery should be chosen on individual situations.