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A Cross-sectional Study On Abnormal Glucose Regulation In Middle-aged And Elderly Residents From Baoding City

Posted on:2010-09-04Degree:MasterType:Thesis
Country:ChinaCandidate:W X LiuFull Text:PDF
GTID:2144360275469606Subject:Epidemiology and Health Statistics
Abstract/Summary:PDF Full Text Request
Objective:In order to assess the prevalence of Type 2 Diabetes Mellitus (T2DM)and Impaired glucose regulation (IGR), and the distribution of the main behavioral factors and physical factors in middle-aged and elderly residents from Baoding city; to identify the main risk factors of the progress of Abnormal glucose regulation,and evaluate the risk of these factors; to provide scientific evidence and suggestion for conducting T2DM preventive programe, and improve the quality of their life.Method: A sample of 3212 community residents(3102 were valid)aged over 40 years old was from three communities which were selected from all communities of Baoding by random cluster sampling. The survey was conducted by trained investigators using a standardized questionnaire, each of the subjects also received physical examination and laboratory test, such as SBP,SDP,TC,TG,LDL-C,HDL-C,WHR,FBG,2hPG and BMI. At every stage of the survey,corresponding quality control measures were used. All the data were entered into computer by Epidata 3.1 and analyzed by SPSS 16.0, Accumulative Logistic Regression was used for the data analysis.Result: The prevalence of T2DM was 21.99%, and detection rate was 8.19%. The prevalence of IGR was 9.15%, including which of 1-IFG,1-IGT and IFG/IGT was 1.58%, 6.25% and 1.32%. And the standardized prevalence by age and gender composition from the census data in Baoding in 2000 of T2DM,1-IFG,1-IGT and IFG/IGT was 19.03%,1.42%,5.92% and 1.34% respectively.The Accumulative Logistic Regression (α=0.05)was used to analyze the association between the progress of Abnormal glucose regulation and the related variables. The result demonstrated that gender,age,engaged in technical work,consumption of fruit,ill temper or irritability, BMI,WC,WHR,SBP,TG,DM family history were significantly associated with the progress of Abnormal glucose regulation. Among them, female and a high consumption of fruit were protective factors. In addition, Reproductive history of fetal macrosomia was an independent risk factor of the progress of Abnormal glucose regulation to female. The study also showed that the prevalence of IGR and T2DM increased with the risk factors were gathered.There were significant differences about the prevalence of T2DM and 1-IGT between the male(26.14% and 7.70%) and the female(19.19% and 5.28%); The prevalence of T2DM and 1-IGT increased with age( trendχ2 = 93.235a nd 16.645, P<0.005), which was highest in the group aged 55 years and over. Apart from age, the main risk factors of the progress of Abnormal glucose regulation were DM family history, obesity especially central obesity,hypertension,hyperlipidemia,etc. The prevalence of overweight and obesity was 27.85% and 45.87%, and the standardized ones were 27.71% and 46.28%. There were significant differences about the prevalence between the male(29.83% and 48.12%) and the female(26.52% and 44.37%); There were also significant differences about the prevalence among different age groups( P < 0.005). The prevalence of central obesity was 57.67%, and the standardized one was 56.03%, There was significant difference about the prevalence between the male(66.16%) and the female(51.97%); the prevalence of central obesity increased with age ( trendχ2 = 91.453, P< 0.005). The prevalence of hypertension was 50.16%, and the standardized one was 46.97%. There was significant difference about the prevalence between the male(55.73%) and the female(46.42%). The prevalence of hyperlipidemia was 44.10%, and the standardized one was 44.09%. There was aslo significant difference about the prevalence between the male(46.11%) and the female(42.75%). The prevalence of hypertension and hyperlipidemia increased with age ( trendχ2 = 124.091a nd 6.169, P<0.05).41.64% of the T2DM patients had complications, the prevalence of coronary artery and cerebral vessels disease was highest(30.35%), the next was DR(18.48%). At the same time, it was common (47.18%) that the diabetic had more than one kind of complication.The awareness of Diabete-related knowledge among the residents was only 40%-70%, they were lack of information about prevention of diabete and the range of normal blood-sugar, especially about IGR. Besides, those who with better education knew more about Diabete-related knowledge.Conclusion:1. The prevalent level of T2DM was high, 27.72% of the residents over 40 years old in Baoding were troubled with Abnormal glucose regulation. All the prevalent levels of overweight and obesity, central obesity, hypertension and hyperlipidemia were high.2. The risk factors of the progress of Abnormal glucose regulation were DM family history,increased age, obesity(BMI), central obesity(WC and WHR),hypertension(SBP) and hyperlipidemia (TG), engaged in technical work,male,ill temper or irritability, and reproductive history of fetal macrosomia to female only.3. The prevalence of coronary artery and cerebral vessels disease was the highest among all the complications of diabetes. Also, it was common that the diabetic had more than one kind of compIication.4. The residents'awareness of Diabete-related knowledge was poor, those who with better education knew more about Diabete-related knowledge.5. The detection rate of diabetic was high, so we should enhance the health census and the screening in high-risk groups in the future.
Keywords/Search Tags:Abnormal glucose regulation, prevalence, risk factors, Accumulative Logistic Regression, detection rate
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