Pre-eclampsia-eclampsia In Patients With Coagulation Parameters And Platelet Changes

Objective:To investigate the pre-eclampsia - pre-eclampsia in patients with coagulation and platelet parameters associated with the disease.Methods:The cause of pregnancy-induced hypertension disease is not yet completely clear, both at home and abroad focused on the major pre-eclampsia - eclampsia Etiology and pathogenesis,this study focuses on pre-eclampsia - eclampsia indicators in patients with blood clotting and platelet parameters change.On January 2004 to August 2008 First Hospital of Shanxi Medical University,example of Obstetrics and Gynecology 410 preeclampsia patients (91 cases including 319 cases of mild and severe) and 20 examples of the four epileptic patients with clotting prothrombin time(PT),activated partial thromboplastin time(APTT),international normalized ratio(INR),fibrinogen(FIB) and platelet series of platelet(PLT),mean platelet volume(MPV),platelet distribution width(PDW) for statistical data analysis,and set the conditions of 100 cases similar to normal late pregnant women for the control group.Results:mild preeclampsia,sub-line of -eclampsia in patients with severe and the PLT,APTT,PT values lower than normal late pregnant women(P＜0.05),MPV,PDW and FIB values higher than the normal late pregnant women(P＜0.05),INR lower than the normal third trimester women(P＞0.05).As the disease worsens,these differences more clearly.In addition,see the cases of five cases was also found to be in a serious condition in patients with APTT,PT extended,FIB reduction,analysis may be the reason of the pregnancy-induced hypertension is a serious disease process has been in existence for chronic DIC,clotting factor consumption,suggesting more serious illness.Conclusion:The clinical detection of pregnancy-induced hypertension through the blood coagulation indicators of disease and platelet parameters,understanding pregnancy-induced hypertension in patients with coagulation diseases will help to determine the severity of the disease,and for the development of treatment programs to provide a help.